Agrin and the organization of the neuromuscular junction
Agrin is a component of the synaptic extracellular matrix and may regulate the organization of acetylcholine receptors and other synaptic molecules in both synapse regeneration and development. Analyses of cDNAs encoding agrin define a number of structural domains, including regions of homology to l...
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Veröffentlicht in: | Current opinion in neurobiology 1992-02, Vol.2 (1), p.88-93 |
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creator | Rupp, Fabio Hoch, Werner Campanelli, James T. Kreiner, Thane Scheller, Richard H. |
description | Agrin is a component of the synaptic extracellular matrix and may regulate the organization of acetylcholine receptors and other synaptic molecules in both synapse regeneration and development. Analyses of cDNAs encoding agrin define a number of structural domains, including regions of homology to laminin, Kazal protease inhibitors, and epidermal growth factor repeats. |
doi_str_mv | 10.1016/0959-4388(92)90168-K |
format | Article |
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subjects | Agrin Animals Extracellular Matrix - physiology Humans Nerve Tissue Proteins - physiology Neuromuscular Junction - physiology Neuromuscular Junction - ultrastructure Receptors, Cholinergic - physiology |
title | Agrin and the organization of the neuromuscular junction |
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