Agrin and the organization of the neuromuscular junction

Agrin and the organization of the neuromuscular junction

Agrin is a component of the synaptic extracellular matrix and may regulate the organization of acetylcholine receptors and other synaptic molecules in both synapse regeneration and development. Analyses of cDNAs encoding agrin define a number of structural domains, including regions of homology to l...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Current opinion in neurobiology 1992-02, Vol.2 (1), p.88-93
Hauptverfasser: Rupp, Fabio, Hoch, Werner, Campanelli, James T., Kreiner, Thane, Scheller, Richard H.
Format: Artikel
Sprache:eng
Schlagworte:
Agrin
Animals
Extracellular Matrix - physiology
Humans
Nerve Tissue Proteins - physiology
Neuromuscular Junction - physiology
Neuromuscular Junction - ultrastructure
Receptors, Cholinergic - physiology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Agrin is a component of the synaptic extracellular matrix and may regulate the organization of acetylcholine receptors and other synaptic molecules in both synapse regeneration and development. Analyses of cDNAs encoding agrin define a number of structural domains, including regions of homology to laminin, Kazal protease inhibitors, and epidermal growth factor repeats.
ISSN:0959-4388
1873-6882
DOI:10.1016/0959-4388(92)90168-K