A Case of Malignant Lymphoma Accompanied by Klinefelter's Syndrome

A 66-year-old Japanese male with diffuse non-Hodgkin's lymphoma, of the pleomorphic type, complicated with Klinefelter's syndrome is reported. His phisique was characterized by a long arm span, disproportionately longer lower body dimensions and a small sized penis. He had no children. Chr...

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Veröffentlicht in:	Internal Medicine 1992, Vol.31(4), pp.496-499
Hauptverfasser:	KOYAMA, Michiko, UEJIMA, Kazuo, KONISHI, Tomotsugu, ISHIDA, Moriharu, KATO, Motokazu, NISHIGAKI, Masamori, MIZUTANI, Hajime, MATSUMOTO, Kyouichiro, KAWASE, Mataemon, TAMAKI, Toshiharu
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged chromosome abnormality Humans Klinefelter Syndrome - complications Klinefelter Syndrome - genetics Lymphoma, Non-Hodgkin - complications Lymphoma, Non-Hodgkin - genetics Lymphoma, Non-Hodgkin - pathology Male non-Hodgkin's lymphoma oncogenesis
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Zusammenfassung:	A 66-year-old Japanese male with diffuse non-Hodgkin's lymphoma, of the pleomorphic type, complicated with Klinefelter's syndrome is reported. His phisique was characterized by a long arm span, disproportionately longer lower body dimensions and a small sized penis. He had no children. Chromosomal study revealed 47, XXY and hormonal quantification showed hypergonadtropic hypogonadism. Although chemotherapy was administered, his disease took a progressive course and he died. A discussion of chromosomal alteration and oncogenesis and review of the literature are included. (Internal Medicine 31 : 496-499, 1992)
ISSN:	0918-2918 1349-7235
DOI:	10.2169/internalmedicine.31.496