The in vitro susceptibility of Scedosporium prolificans to ajoene, allitridium and a raw extract of garlic (Allium sativum)

The in vitro susceptibility of 20 medical isolates of Scedosporium prolificans to ajoene, allitridium and raw garlic extract derived from cloves of garlic (Allium sativum) was tested using the NCCLS reference method (with minor modifications) for broth microdilution. The results demonstrate that bot...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2003-03, Vol.51 (3), p.593-597
Hauptverfasser:	Davis, Stephen R., Perrie, Rosemary, Apitz-Castro, Rafael
Format:	Artikel
Sprache:	eng
Schlagworte:	ajoene allitridium Allyl Compounds - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents antifungal Antifungal agents Antifungal Agents - isolation & purification Antifungal Agents - pharmacology Biological and medical sciences Disulfides - pharmacology Garlic General pharmacology Humans Medical sciences Microbial Sensitivity Tests - statistics & numerical data Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Structures Scedosporium - drug effects Scedosporium - isolation & purification Sulfides - pharmacology
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Zusammenfassung:	The in vitro susceptibility of 20 medical isolates of Scedosporium prolificans to ajoene, allitridium and raw garlic extract derived from cloves of garlic (Allium sativum) was tested using the NCCLS reference method (with minor modifications) for broth microdilution. The results demonstrate that both garlic derivatives and raw garlic extract appear to have in vitro activity against S. prolificans.
ISSN:	0305-7453 1460-2091 1460-2091
DOI:	10.1093/jac/dkg144