In Vitro Selection and Characterization of Hepatitis C Virus Serine Protease Variants Resistant to an Active-Site Peptide Inhibitor

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Veröffentlicht in:	Journal of Virology 2003-03, Vol.77 (6), p.3669-3679
Hauptverfasser:	Trozzi, Caterina, Bartholomew, Linda, Ceccacci, Alessandra, Biasiol, Gabriella, Pacini, Laura, Altamura, Sergio, Narjes, Frank, Muraglia, Ester, Paonessa, Giacomo, Koch, Uwe, De Francesco, Raffaele, Steinkuhler, Christian, Migliaccio, Giovanni
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites - drug effects Carrier Proteins - antagonists & inhibitors Carrier Proteins - drug effects Carrier Proteins - genetics Drug Resistance, Viral - genetics Genetic Variation Hepacivirus - drug effects Hepacivirus - enzymology Hepacivirus - genetics Humans Intracellular Signaling Peptides and Proteins Microbial Sensitivity Tests Models, Molecular Mutation Replicon Selection, Genetic Serine Proteinase Inhibitors - pharmacology Tumor Cells, Cultured Vaccines and Antiviral Agents Viral Nonstructural Proteins - antagonists & inhibitors Viral Nonstructural Proteins - drug effects Viral Nonstructural Proteins - genetics Viral Proteins - antagonists & inhibitors Viral Proteins - drug effects Viral Proteins - genetics
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Zusammenfassung:	Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue JVI About JVI Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy JVI RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0022-538X Online ISSN: 1098-5514 Copyright © 2014 by the American Society for Microbiology. For an alternate route to JVI .asm.org, visit: JVI
ISSN:	0022-538X 1098-5514
DOI:	10.1128/JVI.77.6.3669-3679.2003