Mid-dermal elastolysis with inflammation

A 71-year-old white woman had finely wrinkled, erythematous patches of skin that met the clinical and histologic criteria for mid-dermal elastolysis. In addition to the loss of mid-dermal elastin described in previous cases, histopathologic examination revealed a superficial and deep perivascular in...

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Veröffentlicht in:	Journal of the American Academy of Dermatology 1992-05, Vol.26 (5), p.882-884
Hauptverfasser:	Brod, Bruce A., Rabkin, Michael, Rhodes, Arthur R., Jegasothy, Brian V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Atrophy - etiology Biological and medical sciences Cutis Laxa - complications Cutis Laxa - diagnosis Cutis Laxa - pathology Dermatitis - complications Dermatitis - diagnosis Dermatitis - pathology Dermatology Elastic Tissue - pathology Erythema - complications Erythema - diagnosis Erythema - pathology Female Forearm Humans Leg Dermatoses - complications Leg Dermatoses - diagnosis Leg Dermatoses - pathology Medical sciences Skin - pathology Skin involvement in other diseases. Miscellaneous. General aspects Thigh
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Zusammenfassung:	A 71-year-old white woman had finely wrinkled, erythematous patches of skin that met the clinical and histologic criteria for mid-dermal elastolysis. In addition to the loss of mid-dermal elastin described in previous cases, histopathologic examination revealed a superficial and deep perivascular inflammatory infiltrate of lymphocytes and plasma cells and interstitial collections of multinucleated giant cells containing phagocytized elastin. These results support a previously postulated inflammatory pathogenesis for mid-dermal elastolysis.
ISSN:	0190-9622 1097-6787
DOI:	10.1016/0190-9622(92)70129-4