Cell surface CD43 determination improves diagnostic precision in late B‐cell diseases

Panels of immunological markers are useful in refining diagnosis in view of certain variability between B‐cell leukaemias. A statistical multivariate approach was used on 100 B leukaemias (preliminary sample) to explore the potential value of the combination of CD43, and the classical markers CD5, C...

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Veröffentlicht in:British journal of haematology 2003-02, Vol.120 (3), p.496-499
Hauptverfasser: Jung, Georges, Eisenmann, Jean‐Claude, Thiébault, Sylvie, Hénon, Philippe
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container_title British journal of haematology
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creator Jung, Georges
Eisenmann, Jean‐Claude
Thiébault, Sylvie
Hénon, Philippe
description Panels of immunological markers are useful in refining diagnosis in view of certain variability between B‐cell leukaemias. A statistical multivariate approach was used on 100 B leukaemias (preliminary sample) to explore the potential value of the combination of CD43, and the classical markers CD5, CD23, CD79b, FMC7, CD22 and surface immunoglobulin to differentiate chronic lymphoid leukaemia (CLL) from lymphoma (non‐CLL). CD43 was highly effective (P 
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subjects Antigens, CD
Antigens, Neoplasm - analysis
B-Lymphocytes - immunology
Biological and medical sciences
Biomarkers, Tumor - analysis
CD43
Diagnosis, Differential
Hematologic and hematopoietic diseases
Hematology
Humans
immunophenotype
Immunophenotyping
Leukemia, B-Cell - diagnosis
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Leukosialin
Lymphoma, B-Cell - diagnosis
lymphoproliferative disorder
Medical sciences
Multivariate Analysis
Neoplasm Proteins - analysis
Sialoglycoproteins - analysis
title Cell surface CD43 determination improves diagnostic precision in late B‐cell diseases
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