Growth Hormone Action on Proliferation and Differentiation of Cerebral Cortical Cells from Fetal Rat

To define the role of GH during central nervous system development, we performed studies in cultured rat cerebral cortical cells from 14- (E14) and 17-d-old embryos (E17). The expression of GH receptor, IGF-I receptor, and IGF-I mRNAs was confirmed. In E17, GH increased total cell number (3.9-fold),...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Endocrinology (Philadelphia) 2003-03, Vol.144 (3), p.1086-1097
Hauptverfasser:	Ajo, Rocío, Cacicedo, Lucinda, Navarro, Constanza, Sánchez-Franco, Franco
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antisera Astrocytes - cytology Biological and medical sciences Bromodeoxyuridine Cell differentiation Cell Differentiation - drug effects Cell Division - drug effects Cell number Cell proliferation Cells, Cultured Central nervous system Cerebral Cortex - chemistry Cerebral Cortex - cytology Cerebral Cortex - embryology Differentiation Embryos Female Fetuses Fundamental and applied biological sciences. Psychology Gene Expression Gestational Age Glial fibrillary acidic protein Glial Fibrillary Acidic Protein - analysis Gliogenesis Growth Hormone - pharmacology Growth hormones Insulin-Like Growth Factor Binding Protein 3 - genetics Insulin-like growth factor I Insulin-Like Growth Factor I - genetics Insulin-like growth factor-binding protein 3 Nestin Neural stem cells Neurogenesis Neuronal-glial interactions Neurons - cytology Phosphorylation Pregnancy Proliferating cell nuclear antigen Protein folding Proteins Rats Rats, Wistar Receptor, IGF Type 1 - genetics Receptor, IGF Type 1 - metabolism Receptors Receptors, Somatotropin - genetics RNA, Messenger - analysis Thymidine Tubulin Tubulin - analysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!