Hemi-naevus of Ota: perturbation of neural crest differentiation as a likely mechanism

We present a case of oculodermal melanosis that involves the lower eyelid and lower half of the globe in a very clearly defined fashion. We suggest that such a lesion is the result of a local change in embryonic environment occurring during a well-defined stage of ocular development, such that diffe...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Graefe's archive for clinical and experimental ophthalmology 1992-05, Vol.230 (3), p.226-229
Hauptverfasser: BENSON, M. T, RENNIE, I. G
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 229
container_issue 3
container_start_page 226
container_title Graefe's archive for clinical and experimental ophthalmology
container_volume 230
creator BENSON, M. T
RENNIE, I. G
description We present a case of oculodermal melanosis that involves the lower eyelid and lower half of the globe in a very clearly defined fashion. We suggest that such a lesion is the result of a local change in embryonic environment occurring during a well-defined stage of ocular development, such that differentiation of neural crest cells into a melanocytic phenotype is favoured.
doi_str_mv 10.1007/BF00176293
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72977801</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72977801</sourcerecordid><originalsourceid>FETCH-LOGICAL-c226t-ec72ad0070f562d6c042ec998efcf2d5b811edc102c5ad6ececff6f4c0a436c53</originalsourceid><addsrcrecordid>eNpFkMtLw0AQhxdRaq1evAt7EA9CdHbz2MSbFmuFQi8qvYXtZBZX86i7idD_3pQUexqY72MeP8YuBdwJAHX_NAMQKpFZeMTGIgrjQIFcHbMxKCmCNJSrU3bm_RcA9FCM2EjEmZJpMmYfc6psUGv67TxvDF-2-oFvyLWdW-vWNvWuWVPndMnRkW95YY0hR3VrB64917y031RueUX4qWvrq3N2YnTp6WJfJ-x99vw2nQeL5cvr9HERoJRJGxAqqYv-BTBxIosEIZKEWZaSQSOLeJ0KQQUKkBjrIiEkNCYxEYKOwgTjcMJuhrkb1_x0_Xl5ZT1SWeqams7nSmZKpSB68XYQ0TXeOzL5xtlKu20uIN-FmB9C7OWr_dRuXVFxUIfUen6959qjLo3TNVr_r8UyzcJ-5x8M5HoS</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72977801</pqid></control><display><type>article</type><title>Hemi-naevus of Ota: perturbation of neural crest differentiation as a likely mechanism</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>BENSON, M. T ; RENNIE, I. G</creator><creatorcontrib>BENSON, M. T ; RENNIE, I. G</creatorcontrib><description>We present a case of oculodermal melanosis that involves the lower eyelid and lower half of the globe in a very clearly defined fashion. We suggest that such a lesion is the result of a local change in embryonic environment occurring during a well-defined stage of ocular development, such that differentiation of neural crest cells into a melanocytic phenotype is favoured.</description><identifier>ISSN: 0721-832X</identifier><identifier>EISSN: 1435-702X</identifier><identifier>DOI: 10.1007/BF00176293</identifier><identifier>PMID: 1597286</identifier><identifier>CODEN: GACODL</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Adult ; Biological and medical sciences ; Cell Division ; Eye - embryology ; Eye Neoplasms - pathology ; Eyelid Neoplasms - pathology ; Female ; Fundus Oculi ; Humans ; Iris Neoplasms - pathology ; Malformations of the eye ; Medical sciences ; Melanosis - pathology ; Neural Crest - pathology ; Nevus of Ota - pathology ; Ophthalmology</subject><ispartof>Graefe's archive for clinical and experimental ophthalmology, 1992-05, Vol.230 (3), p.226-229</ispartof><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c226t-ec72ad0070f562d6c042ec998efcf2d5b811edc102c5ad6ececff6f4c0a436c53</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27911,27912</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=5289301$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1597286$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BENSON, M. T</creatorcontrib><creatorcontrib>RENNIE, I. G</creatorcontrib><title>Hemi-naevus of Ota: perturbation of neural crest differentiation as a likely mechanism</title><title>Graefe's archive for clinical and experimental ophthalmology</title><addtitle>Graefes Arch Clin Exp Ophthalmol</addtitle><description>We present a case of oculodermal melanosis that involves the lower eyelid and lower half of the globe in a very clearly defined fashion. We suggest that such a lesion is the result of a local change in embryonic environment occurring during a well-defined stage of ocular development, such that differentiation of neural crest cells into a melanocytic phenotype is favoured.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cell Division</subject><subject>Eye - embryology</subject><subject>Eye Neoplasms - pathology</subject><subject>Eyelid Neoplasms - pathology</subject><subject>Female</subject><subject>Fundus Oculi</subject><subject>Humans</subject><subject>Iris Neoplasms - pathology</subject><subject>Malformations of the eye</subject><subject>Medical sciences</subject><subject>Melanosis - pathology</subject><subject>Neural Crest - pathology</subject><subject>Nevus of Ota - pathology</subject><subject>Ophthalmology</subject><issn>0721-832X</issn><issn>1435-702X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMtLw0AQhxdRaq1evAt7EA9CdHbz2MSbFmuFQi8qvYXtZBZX86i7idD_3pQUexqY72MeP8YuBdwJAHX_NAMQKpFZeMTGIgrjQIFcHbMxKCmCNJSrU3bm_RcA9FCM2EjEmZJpMmYfc6psUGv67TxvDF-2-oFvyLWdW-vWNvWuWVPndMnRkW95YY0hR3VrB64917y031RueUX4qWvrq3N2YnTp6WJfJ-x99vw2nQeL5cvr9HERoJRJGxAqqYv-BTBxIosEIZKEWZaSQSOLeJ0KQQUKkBjrIiEkNCYxEYKOwgTjcMJuhrkb1_x0_Xl5ZT1SWeqams7nSmZKpSB68XYQ0TXeOzL5xtlKu20uIN-FmB9C7OWr_dRuXVFxUIfUen6959qjLo3TNVr_r8UyzcJ-5x8M5HoS</recordid><startdate>199205</startdate><enddate>199205</enddate><creator>BENSON, M. T</creator><creator>RENNIE, I. G</creator><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199205</creationdate><title>Hemi-naevus of Ota: perturbation of neural crest differentiation as a likely mechanism</title><author>BENSON, M. T ; RENNIE, I. G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c226t-ec72ad0070f562d6c042ec998efcf2d5b811edc102c5ad6ececff6f4c0a436c53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Cell Division</topic><topic>Eye - embryology</topic><topic>Eye Neoplasms - pathology</topic><topic>Eyelid Neoplasms - pathology</topic><topic>Female</topic><topic>Fundus Oculi</topic><topic>Humans</topic><topic>Iris Neoplasms - pathology</topic><topic>Malformations of the eye</topic><topic>Medical sciences</topic><topic>Melanosis - pathology</topic><topic>Neural Crest - pathology</topic><topic>Nevus of Ota - pathology</topic><topic>Ophthalmology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BENSON, M. T</creatorcontrib><creatorcontrib>RENNIE, I. G</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Graefe's archive for clinical and experimental ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BENSON, M. T</au><au>RENNIE, I. G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hemi-naevus of Ota: perturbation of neural crest differentiation as a likely mechanism</atitle><jtitle>Graefe's archive for clinical and experimental ophthalmology</jtitle><addtitle>Graefes Arch Clin Exp Ophthalmol</addtitle><date>1992-05</date><risdate>1992</risdate><volume>230</volume><issue>3</issue><spage>226</spage><epage>229</epage><pages>226-229</pages><issn>0721-832X</issn><eissn>1435-702X</eissn><coden>GACODL</coden><abstract>We present a case of oculodermal melanosis that involves the lower eyelid and lower half of the globe in a very clearly defined fashion. We suggest that such a lesion is the result of a local change in embryonic environment occurring during a well-defined stage of ocular development, such that differentiation of neural crest cells into a melanocytic phenotype is favoured.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>1597286</pmid><doi>10.1007/BF00176293</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0721-832X
ispartof Graefe's archive for clinical and experimental ophthalmology, 1992-05, Vol.230 (3), p.226-229
issn 0721-832X
1435-702X
language eng
recordid cdi_proquest_miscellaneous_72977801
source MEDLINE; Springer Nature - Complete Springer Journals
subjects Adult
Biological and medical sciences
Cell Division
Eye - embryology
Eye Neoplasms - pathology
Eyelid Neoplasms - pathology
Female
Fundus Oculi
Humans
Iris Neoplasms - pathology
Malformations of the eye
Medical sciences
Melanosis - pathology
Neural Crest - pathology
Nevus of Ota - pathology
Ophthalmology
title Hemi-naevus of Ota: perturbation of neural crest differentiation as a likely mechanism
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T16%3A50%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Hemi-naevus%20of%20Ota:%20perturbation%20of%20neural%20crest%20differentiation%20as%20a%20likely%20mechanism&rft.jtitle=Graefe's%20archive%20for%20clinical%20and%20experimental%20ophthalmology&rft.au=BENSON,%20M.%20T&rft.date=1992-05&rft.volume=230&rft.issue=3&rft.spage=226&rft.epage=229&rft.pages=226-229&rft.issn=0721-832X&rft.eissn=1435-702X&rft.coden=GACODL&rft_id=info:doi/10.1007/BF00176293&rft_dat=%3Cproquest_cross%3E72977801%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=72977801&rft_id=info:pmid/1597286&rfr_iscdi=true