Hemi-naevus of Ota: perturbation of neural crest differentiation as a likely mechanism

We present a case of oculodermal melanosis that involves the lower eyelid and lower half of the globe in a very clearly defined fashion. We suggest that such a lesion is the result of a local change in embryonic environment occurring during a well-defined stage of ocular development, such that diffe...

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Veröffentlicht in:	Graefe's archive for clinical and experimental ophthalmology 1992-05, Vol.230 (3), p.226-229
Hauptverfasser:	BENSON, M. T, RENNIE, I. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cell Division Eye - embryology Eye Neoplasms - pathology Eyelid Neoplasms - pathology Female Fundus Oculi Humans Iris Neoplasms - pathology Malformations of the eye Medical sciences Melanosis - pathology Neural Crest - pathology Nevus of Ota - pathology Ophthalmology
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Beschreibung
Zusammenfassung:	We present a case of oculodermal melanosis that involves the lower eyelid and lower half of the globe in a very clearly defined fashion. We suggest that such a lesion is the result of a local change in embryonic environment occurring during a well-defined stage of ocular development, such that differentiation of neural crest cells into a melanocytic phenotype is favoured.
ISSN:	0721-832X 1435-702X
DOI:	10.1007/BF00176293