Immunogenic measles antigens expressed in plants: role as an edible vaccine for adults

Vaccine-induced immunity against measles is less robust than natural immunity. Waning of immunity in vaccines may eventually require a revaccination of adults. Measles antigens expressed in plants have been shown to be antigenic and immunogenic both after invasive and oral vaccination. Strategies fo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2003-01, Vol.21 (7), p.816-819
Hauptverfasser:	Muller, Claude P, Fack, Fred, Damien, Benjamin, Bouche, Fabienne B
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Animals Antigens, Viral - biosynthesis Antigens, Viral - genetics Biological and medical sciences Fundamental and applied biological sciences. Psychology Humans Infections Lymphocytes Measles - prevention & control Measles Vaccine - administration & dosage Measles Vaccine - immunology Measles virus Microbiology Oral vaccine Plants, Genetically Modified - genetics Plants, Genetically Modified - metabolism Polyepitope Proteins Tobacco Transgenic carrots Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Vaccines, Edible - administration & dosage Vaccines, Edible - immunology Virology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Vaccine-induced immunity against measles is less robust than natural immunity. Waning of immunity in vaccines may eventually require a revaccination of adults. Measles antigens expressed in plants have been shown to be antigenic and immunogenic both after invasive and oral vaccination. Strategies for the vaccination of adults, the potential of an oral measles vaccine produced in edible plants and the design of suitable antigens are discussed.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/S0264-410X(02)00606-0