Post-translational chemical modification(S) of proteins

1. 1. The role played by the modification of protein in determining its fate is reported by us. 2. 2. Post-translational modifications such as acetylation, phosphorylation, sulfation, methylation, hydroxylation, ADP-ribosylation, maturation, amidation, carboxylation, adenylylation, glycosylation, ub...

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Veröffentlicht in:International Journal of Biochemistry 1992, Vol.24 (1), p.19-28
Hauptverfasser: Kia-Ki, Han, Martinage, Arlette
Format: Artikel
Sprache:eng
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Zusammenfassung:1. 1. The role played by the modification of protein in determining its fate is reported by us. 2. 2. Post-translational modifications such as acetylation, phosphorylation, sulfation, methylation, hydroxylation, ADP-ribosylation, maturation, amidation, carboxylation, adenylylation, glycosylation, ubiquitination, and prenylation are extensively reviewed. 3. 3. Each post-translational modification's significance and its role played in biological function(s) is summarized in the general discussion and the conclusion's remark is directed at the problems left to solve (e.g. post-translational modification reactions in recombinant protein in modern genetic engineering).
ISSN:0020-711X
DOI:10.1016/0020-711X(92)90225-P