DNA Repair: Bacteria Join In

In higher organisms, a major pathway for repairing double stranded breaks in DNA is non-homologous end-joining. Now a similar pathway has been shown to operate in bacterial cells, indicating that this important repair mechanism has been conserved through evolution.

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Bibliographische Detailangaben
Veröffentlicht in:	Current biology 2003-01, Vol.13 (1), p.R28-R30
1. Verfasser:	Hiom, Kevin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Nuclear - physiology Bacteria - genetics Bacterial Proteins - genetics Bacterial Proteins - metabolism DNA Helicases DNA Ligase ATP DNA Ligases - genetics DNA Ligases - metabolism DNA Repair - physiology DNA-Binding Proteins - physiology Ku Autoantigen Mammals - genetics
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Beschreibung
Zusammenfassung:	In higher organisms, a major pathway for repairing double stranded breaks in DNA is non-homologous end-joining. Now a similar pathway has been shown to operate in bacterial cells, indicating that this important repair mechanism has been conserved through evolution.
ISSN:	0960-9822 1879-0445
DOI:	10.1016/S0960-9822(02)01385-4