Effects of thioredoxin on the preimplantation development of bovine embryos

Thioredoxin (TRX) is an ubiquitous protein disulfide reductase, which is known to be involved in the implantation development of mouse embryos. In the present study, recombinant human TRX was used to evaluate its effect on the promotion of preimplantation development of bovine embryos derived from i...

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Veröffentlicht in:	Theriogenology 2003-02, Vol.59 (3), p.863-873
Hauptverfasser:	Bing, Y.Z., Hirao, Y., Takenouchi, N., Che, L.M., Nakamura, H., Yodoi, J., Nagai, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blastocyst - drug effects Blastocyst - physiology Bovine Cattle - embryology Culture Media Culture Techniques Dose-Response Relationship, Drug Embryo development Embryonic and Fetal Development - drug effects Female Fertilization in Vitro - veterinary First cleavage stage Oxidation-Reduction Oxygen - metabolism Thioredoxin (TRX) Thioredoxins - pharmacology
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Beschreibung
Zusammenfassung:	Thioredoxin (TRX) is an ubiquitous protein disulfide reductase, which is known to be involved in the implantation development of mouse embryos. In the present study, recombinant human TRX was used to evaluate its effect on the promotion of preimplantation development of bovine embryos derived from in vitro maturation and fertilization. Supplementation of the medium 24 h post insemination with TRX significantly ( P
ISSN:	0093-691X 1879-3231
DOI:	10.1016/S0093-691X(02)01158-5