Volume-cycled decelerating flow. An alternative form of mechanical ventilation
The linearly decelerating flow waveform for volume-cycled mechanical ventilation is an option on many modern ventilators. We have developed mathematical models for two available forms of volume-cycled decelerating-flow ventilation (VCDF). These equations use clinician-chosen ventilator settings as i...
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Veröffentlicht in: | Chest 1992-05, Vol.101 (5), p.1342-1351 |
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Zusammenfassung: | The linearly decelerating flow waveform for volume-cycled mechanical ventilation is an option on many modern ventilators.
We have developed mathematical models for two available forms of volume-cycled decelerating-flow ventilation (VCDF). These
equations use clinician-chosen ventilator settings as inputs (frequency, tidal volume, peak inspiratory flow or inspiratory
time fraction, and end-inspiratory pause), and patient-determined inputs which describe the patient's ventilatory impedance
(inspiratory [RI] and expiratory [RE] resistance and respiratory system compliance [C]. The equations predict key outcome
variables: mean airway pressure; and peak, mean, and end-expiratory alveolar pressures. The mathematical expressions were
validated in a mechanical lung analog. Values observed in the test lung were compared to values predicted by the mathematical
models for a wide range of ventilator settings and impedance combinations (RI and RE, 5 to 40 cm H2O.s/L; C, 0.02 to 0.10
L/cm H2O). The correspondence between observed and predicted values was generally excellent across the broad range of inputs
tested (r greater than or equal to 0.98). Outcome variables were quite sensitive to clinician-chosen inputs over certain critical
ranges. Carefully applied, VCDF offers several theoretic advantages for the clinical setting; however, appropriate caution
must be exercised to avoid the application of tissue-injuring pressure. |
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ISSN: | 0012-3692 1931-3543 |
DOI: | 10.1378/chest.101.5.1342 |