Polymorphism of MDR1 Gene in Healthy Japanese Subjects: A Novel SNP with an Amino Acid Substitution (Glu108Lys)

We discovered a novel single nucleotide polymorphism (SNP) at position 325 (G325A) in exon 5 of the multidrug-resistance 1 (MDR1) gene in a study of 37 healthy Japanese subjects. Details are as follows. SNP, 020614Honda001; GENE NAME, human P-glycoprotein (MDR1); ACCESSION NUMBER, M29427; LENGTH, 25...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Drug metabolism and pharmacokinetics 2002, Vol.17 (5), p.479-481
Hauptverfasser:	Honda, Tomohiro, Dan, Yukihiko, Koyabu, Noriko, Ieiri, Ichiro, Otsubo, Kenji, Higuchi, Shun, Ohtani, Hisakazu, Sawada, Yasufumi
Format:	Artikel
Sprache:	eng
Schlagworte:	amino acid substitution exon 5 G325A multidrug-resistance 1 (P-glycoprotein MDR1, ABCB1) single nucleotide polymorphism (SNP)
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!