Quantifying drug-induced changes in Parkinsonian rigidity using an instrumental measure of activated stiffness
We review the literature on quantifying parkinsonian rigidity and present data from 124 subjects to demonstrate the clinical utility of activated stiffness to model rigidity. This method eliminates many of the confounding variables associated with the subjective assessment of rigidity. This 5-min co...
Gespeichert in:
| Veröffentlicht in: | Clinical neuropharmacology 1992-02, Vol.15 (1), p.1-12 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 12 |
|---|---|
| container_issue | 1 |
| container_start_page | 1 |
| container_title | Clinical neuropharmacology |
| container_volume | 15 |
| creator | CALIGIURI, M. P GALASKO, D. R |
| description | We review the literature on quantifying parkinsonian rigidity and present data from 124 subjects to demonstrate the clinical utility of activated stiffness to model rigidity. This method eliminates many of the confounding variables associated with the subjective assessment of rigidity. This 5-min computer-assisted procedure was highly reliable and sensitive to pharmacologic influences that produce and reduce parkinsonian rigidity. |
| doi_str_mv | 10.1097/00002826-199202000-00001 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72922370</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72922370</sourcerecordid><originalsourceid>FETCH-LOGICAL-c339t-1c6e898e17d4a5effd2f5bf626cd1c3bd98bd68cc7c328f1f571500b96dc9a8e3</originalsourceid><addsrcrecordid>eNpFUFtrFDEUDqK02-pPEPIgvk2by-T2WIqtQqEVFHwbMrms0ZlMzZkI---bdbf1vBzOdzvwIYQpuaDEqEvShmkmO2oMI6xd3R6ir9CGCq46KtmP12hDuGSdkLI_RWcAv5pCm96coBMqlBSm36D8tdq8prhLeYt9qdsuZV9d8Nj9tHkbAKeMH2z5nTIsOdmMS9omn9YdrrD3NKRRa6lzyKud8Bws1BLwErF1a_pr15YF7UPMAeAtehPtBOHdcZ-j7zefvl1_7u7ub79cX911jnOzdtTJoI0OVPneihCjZ1GMUTLpPHV89EaPXmrnlONMRxqFooKQ0UjvjNWBn6OPh9zHsvypAdZhTuDCNNkclgqDYoYxrkgT6oPQlQWghDg8ljTbshsoGfZVD89VDy9V_4Nos74__qjjHPx_46Hbxn848hacnWKx2SV4kQlGuJI9fwLJRomK</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72922370</pqid></control><display><type>article</type><title>Quantifying drug-induced changes in Parkinsonian rigidity using an instrumental measure of activated stiffness</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>CALIGIURI, M. P ; GALASKO, D. R</creator><creatorcontrib>CALIGIURI, M. P ; GALASKO, D. R</creatorcontrib><description>We review the literature on quantifying parkinsonian rigidity and present data from 124 subjects to demonstrate the clinical utility of activated stiffness to model rigidity. This method eliminates many of the confounding variables associated with the subjective assessment of rigidity. This 5-min computer-assisted procedure was highly reliable and sensitive to pharmacologic influences that produce and reduce parkinsonian rigidity.</description><identifier>ISSN: 0362-5664</identifier><identifier>EISSN: 1537-162X</identifier><identifier>DOI: 10.1097/00002826-199202000-00001</identifier><identifier>PMID: 1576594</identifier><identifier>CODEN: CLNEDB</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Anticonvulsants. Antiepileptics. Antiparkinson agents ; Antiparkinson Agents - therapeutic use ; Biological and medical sciences ; Female ; Humans ; Male ; Medical sciences ; Middle Aged ; Models, Biological ; Muscle Rigidity - diagnosis ; Muscle Rigidity - drug therapy ; Muscle Rigidity - physiopathology ; Neuropharmacology ; Parkinson Disease - diagnosis ; Parkinson Disease - drug therapy ; Parkinson Disease - physiopathology ; Pharmacology. Drug treatments</subject><ispartof>Clinical neuropharmacology, 1992-02, Vol.15 (1), p.1-12</ispartof><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-1c6e898e17d4a5effd2f5bf626cd1c3bd98bd68cc7c328f1f571500b96dc9a8e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=5203764$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1576594$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>CALIGIURI, M. P</creatorcontrib><creatorcontrib>GALASKO, D. R</creatorcontrib><title>Quantifying drug-induced changes in Parkinsonian rigidity using an instrumental measure of activated stiffness</title><title>Clinical neuropharmacology</title><addtitle>Clin Neuropharmacol</addtitle><description>We review the literature on quantifying parkinsonian rigidity and present data from 124 subjects to demonstrate the clinical utility of activated stiffness to model rigidity. This method eliminates many of the confounding variables associated with the subjective assessment of rigidity. This 5-min computer-assisted procedure was highly reliable and sensitive to pharmacologic influences that produce and reduce parkinsonian rigidity.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anticonvulsants. Antiepileptics. Antiparkinson agents</subject><subject>Antiparkinson Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Models, Biological</subject><subject>Muscle Rigidity - diagnosis</subject><subject>Muscle Rigidity - drug therapy</subject><subject>Muscle Rigidity - physiopathology</subject><subject>Neuropharmacology</subject><subject>Parkinson Disease - diagnosis</subject><subject>Parkinson Disease - drug therapy</subject><subject>Parkinson Disease - physiopathology</subject><subject>Pharmacology. Drug treatments</subject><issn>0362-5664</issn><issn>1537-162X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFUFtrFDEUDqK02-pPEPIgvk2by-T2WIqtQqEVFHwbMrms0ZlMzZkI---bdbf1vBzOdzvwIYQpuaDEqEvShmkmO2oMI6xd3R6ir9CGCq46KtmP12hDuGSdkLI_RWcAv5pCm96coBMqlBSm36D8tdq8prhLeYt9qdsuZV9d8Nj9tHkbAKeMH2z5nTIsOdmMS9omn9YdrrD3NKRRa6lzyKud8Bws1BLwErF1a_pr15YF7UPMAeAtehPtBOHdcZ-j7zefvl1_7u7ub79cX911jnOzdtTJoI0OVPneihCjZ1GMUTLpPHV89EaPXmrnlONMRxqFooKQ0UjvjNWBn6OPh9zHsvypAdZhTuDCNNkclgqDYoYxrkgT6oPQlQWghDg8ljTbshsoGfZVD89VDy9V_4Nos74__qjjHPx_46Hbxn848hacnWKx2SV4kQlGuJI9fwLJRomK</recordid><startdate>19920201</startdate><enddate>19920201</enddate><creator>CALIGIURI, M. P</creator><creator>GALASKO, D. R</creator><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19920201</creationdate><title>Quantifying drug-induced changes in Parkinsonian rigidity using an instrumental measure of activated stiffness</title><author>CALIGIURI, M. P ; GALASKO, D. R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-1c6e898e17d4a5effd2f5bf626cd1c3bd98bd68cc7c328f1f571500b96dc9a8e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anticonvulsants. Antiepileptics. Antiparkinson agents</topic><topic>Antiparkinson Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Models, Biological</topic><topic>Muscle Rigidity - diagnosis</topic><topic>Muscle Rigidity - drug therapy</topic><topic>Muscle Rigidity - physiopathology</topic><topic>Neuropharmacology</topic><topic>Parkinson Disease - diagnosis</topic><topic>Parkinson Disease - drug therapy</topic><topic>Parkinson Disease - physiopathology</topic><topic>Pharmacology. Drug treatments</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>CALIGIURI, M. P</creatorcontrib><creatorcontrib>GALASKO, D. R</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical neuropharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>CALIGIURI, M. P</au><au>GALASKO, D. R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quantifying drug-induced changes in Parkinsonian rigidity using an instrumental measure of activated stiffness</atitle><jtitle>Clinical neuropharmacology</jtitle><addtitle>Clin Neuropharmacol</addtitle><date>1992-02-01</date><risdate>1992</risdate><volume>15</volume><issue>1</issue><spage>1</spage><epage>12</epage><pages>1-12</pages><issn>0362-5664</issn><eissn>1537-162X</eissn><coden>CLNEDB</coden><abstract>We review the literature on quantifying parkinsonian rigidity and present data from 124 subjects to demonstrate the clinical utility of activated stiffness to model rigidity. This method eliminates many of the confounding variables associated with the subjective assessment of rigidity. This 5-min computer-assisted procedure was highly reliable and sensitive to pharmacologic influences that produce and reduce parkinsonian rigidity.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>1576594</pmid><doi>10.1097/00002826-199202000-00001</doi><tpages>12</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0362-5664 |
| ispartof | Clinical neuropharmacology, 1992-02, Vol.15 (1), p.1-12 |
| issn | 0362-5664 1537-162X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_72922370 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adult Aged Aged, 80 and over Anticonvulsants. Antiepileptics. Antiparkinson agents Antiparkinson Agents - therapeutic use Biological and medical sciences Female Humans Male Medical sciences Middle Aged Models, Biological Muscle Rigidity - diagnosis Muscle Rigidity - drug therapy Muscle Rigidity - physiopathology Neuropharmacology Parkinson Disease - diagnosis Parkinson Disease - drug therapy Parkinson Disease - physiopathology Pharmacology. Drug treatments |
| title | Quantifying drug-induced changes in Parkinsonian rigidity using an instrumental measure of activated stiffness |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T19%3A31%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Quantifying%20drug-induced%20changes%20in%20Parkinsonian%20rigidity%20using%20an%20instrumental%20measure%20of%20activated%20stiffness&rft.jtitle=Clinical%20neuropharmacology&rft.au=CALIGIURI,%20M.%20P&rft.date=1992-02-01&rft.volume=15&rft.issue=1&rft.spage=1&rft.epage=12&rft.pages=1-12&rft.issn=0362-5664&rft.eissn=1537-162X&rft.coden=CLNEDB&rft_id=info:doi/10.1097/00002826-199202000-00001&rft_dat=%3Cproquest_cross%3E72922370%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=72922370&rft_id=info:pmid/1576594&rfr_iscdi=true |