Risk factors for failure of Helicobacter pylori therapy — results of an individual data analysis of 2751 patients

Summary Aim : To study risk factors for failure of Helicobacter pylori eradication treatment. Methods : Individual data from 2751 patients included in 11 multicentre clinical trials carried out in France and using a triple therapy, were gathered in a unique database. The 27 treatment regimens were regrouped into four categories. Results : The global failure rate was 25.8%[95% CI: 24–27]. There was a difference in failure rate between duodenal ulcer patients and non‐ulcer dyspeptic patients, 21.9% and 33.7%, respectively (P