Somatic cell mapping of bovine EC-SOD and SOD1L loci

cDNA probes of human extracellular superoxide dismutase (EC-SOD) and bovine superoxide dismutase 1 (SOD1) genes were hybridized to Southern blots containing genomic DNAs from cow-rodent somatic cell lines segregating bovine chromosomes. The SOD1 probe identified two loci: the coding locus (SOD1)), w...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 1992-03, Vol.12 (3), p.610-612
Hauptverfasser:	Gallagher, Daniel S., Gibbs, Lester S., Shaffer, Jacquelin B., Womack, James E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blotting, Southern BOVIN CATTLE Cell Line CHROMOSOME Chromosome Mapping CHROMOSOMES Classical genetics, quantitative genetics, hybrids CROMOSOMAS DNA - genetics DNA - isolation & purification Fundamental and applied biological sciences. Psychology GANADO BOVINO GENE GENE LOCATION GENE MAPPING GENERO HUMANO GENES Genetics of eukaryotes. Biological and molecular evolution GENRE HUMAIN Humans Hybrid Cells LOCALISATION DE GENE LOCALIZACION DE GENES LOCI LOCUS MAN MANKIND SUPEROXIDE DISMUTASE Superoxide Dismutase - genetics SUPEROXIDO DISMUTASA SUPEROXYDE DISMUTASE Vertebrata
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Zusammenfassung:	cDNA probes of human extracellular superoxide dismutase (EC-SOD) and bovine superoxide dismutase 1 (SOD1) genes were hybridized to Southern blots containing genomic DNAs from cow-rodent somatic cell lines segregating bovine chromosomes. The SOD1 probe identified two loci: the coding locus (SOD1)), which mapped to U11. EC-SOD mapped to bovine U15. The mapping of EC-SOD to human chromosome 4, and our mapping of EC-SOD to U15, further defines a region of extensive syntenic conservation between humans and domestic cows.
ISSN:	0888-7543 1089-8646
DOI:	10.1016/0888-7543(92)90457-4