The cost-effectiveness of β-radiation therapy for treatment of in-stent restenosis: An analysis at 290-day follow-up

Purpose: We studied the cost-effectiveness of percutaneous coronary intervention (PCI) plus β-radiation (Radiotherapy) vs. PCI alone for treating in-stent restenosis. Methods and materials: We analyzed medical resource data collected at US sites during the Intimal Hyperplasia Inhibition with β In-stent Trial (INHIBIT) to compare the incremental costs between Radiotherapy and PCI alone for each repeat target lesion revascularization (TLR) avoided. Costs were assigned for cardiac-related medical services using the Medicare payer perspective. Results: Radiotherapy increased initial inpatient costs by US$3360 ( P