Persistent cerebrospinal fluid neutrophilia in delayed-onset neonatal encephalitis caused by herpes simplex virus type 2

We describe an infant with three unusual features of perinatally acquired herpes simplex virus type 2 encephalitis: onset of illness at 34 days of age, absolute cerebrospinal fluid neutrophilia, and systemic viral dissemination after central nervous system disease. To provide early, effective antivi...

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Veröffentlicht in:	The Journal of pediatrics 1992-04, Vol.120 (4), p.567-569
Hauptverfasser:	Silverman, Michael S., Gartner, John G., Halliday, William C., Embree, Joanne
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Encephalitis - blood Encephalitis - cerebrospinal fluid Encephalitis - pathology Female Herpes Simplex - blood Herpes Simplex - cerebrospinal fluid Herpes Simplex - pathology Human viral diseases Humans Immunoenzyme Techniques Infant, Newborn Infectious diseases Leukocyte Count Medical sciences Neutrophils Simplexvirus - isolation & purification Viral diseases Viral diseases of the nervous system
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Beschreibung
Zusammenfassung:	We describe an infant with three unusual features of perinatally acquired herpes simplex virus type 2 encephalitis: onset of illness at 34 days of age, absolute cerebrospinal fluid neutrophilia, and systemic viral dissemination after central nervous system disease. To provide early, effective antiviral therapy, clinicians should be aware of atypical presentations of serious herpes simplex virus infections.
ISSN:	0022-3476 1097-6833
DOI:	10.1016/S0022-3476(05)82485-0