Delta-Positive T-Cell Lymphoma That Produces Interferon Gamma

Delta-Positive T-Cell Lymphoma That Produces Interferon Gamma

To the Editor: The clinicopathologic features of the patient described by Burg et al. (Oct. 10 issue) 1 who had a subcutaneous T-cell lymphoma simulating panniculitis are similar to those of a series of eight patients we recently described. 2 A notable feature of subcutaneous T-cell lymphoma is its...

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Veröffentlicht in:The New England journal of medicine 1992-04, Vol.326 (16), p.1088-1089
Hauptverfasser: Gonzalez, C L, Medeiros, L J, Jaffe, E S
Format: Artikel
Sprache:eng
Schlagworte:
Histiocytosis, Non-Langerhans-Cell - complications
Histiocytosis, Non-Langerhans-Cell - metabolism
Humans
Interferon-gamma - biosynthesis
Lymphoma, T-Cell, Cutaneous - complications
Lymphoma, T-Cell, Cutaneous - metabolism
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container_issue 16
container_start_page 1088
container_title The New England journal of medicine
container_volume 326
creator Gonzalez, C L
Medeiros, L J
Jaffe, E S
description To the Editor: The clinicopathologic features of the patient described by Burg et al. (Oct. 10 issue) 1 who had a subcutaneous T-cell lymphoma simulating panniculitis are similar to those of a series of eight patients we recently described. 2 A notable feature of subcutaneous T-cell lymphoma is its association with a hemophagocytic syndrome, which was the case in six of the patients we described. 2 Although this complication was not described in the patient of Burg et al., 1 the clinical findings of fever and leukopenia suggest this possibility. The apparent production of interferon gamma by the neoplastic cells could be a pathogenetic . . .
doi_str_mv 10.1056/NEJM199204163261614
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subjects Histiocytosis, Non-Langerhans-Cell - complications
Histiocytosis, Non-Langerhans-Cell - metabolism
Humans
Interferon-gamma - biosynthesis
Lymphoma, T-Cell, Cutaneous - complications
Lymphoma, T-Cell, Cutaneous - metabolism
title Delta-Positive T-Cell Lymphoma That Produces Interferon Gamma
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