Solution-Phase Parallel Synthesis of Carbamates Using Polymer-Bound N-Hydroxysuccinimide

Solution-Phase Parallel Synthesis of Carbamates Using Polymer-Bound N-Hydroxysuccinimide

A convenient method for the synthesis of carbamates using polymer-supported N-hydroxysuccinimide is described. Various carbamates were synthesized in highly pure form without the need for chromatographic purification. This new “catch and release”-type solid-phase synthesis should be useful for combi...

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Veröffentlicht in:Organic letters 2002-10, Vol.4 (22), p.3923-3926
Hauptverfasser: Sumiyoshi, Hirokazu, Shimizu, Takafumi, Katoh, Miho, Baba, Yoshiyasu, Sodeoka, Mikiko
Format: Artikel
Sprache:eng
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Zusammenfassung:A convenient method for the synthesis of carbamates using polymer-supported N-hydroxysuccinimide is described. Various carbamates were synthesized in highly pure form without the need for chromatographic purification. This new “catch and release”-type solid-phase synthesis should be useful for combinatorial synthesis of various carbamates.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol026756f