MYCINAMICINS, NEW MACROLIDE ANTIBIOTICS: XIII. ISOLATION AND STRUCTURES OF NOVEL FERMENTATION PRODUCTS FROM Micromonospora griseorubida (FERM BP-705)

Novel 16-membered macrolide antibiotics, mycinamicins IX, XII, XIII, XIV, XV, XVI, XVII and XVIII have been isolated from the culture filtrate of Micromonospora griseorubida (FERM BP-705). Fermentation, isolation, structure determination and biosynthetic consideration of these mycinamicin analogs ar...

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Veröffentlicht in:	Journal of antibiotics 1992/01/25, Vol.45(1), pp.1-9
Hauptverfasser:	KINOSHITA, KENJI, TAKENAKA, SATOSHI, SUZUKI, HIDEAKI, MOROHOSHI, TOSHIRO, HAYASHI, MITSUO
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - biosynthesis Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteria - drug effects Biological and medical sciences Chromatography, High Pressure Liquid Chromatography, Thin Layer Fermentation Macrolides Magnetic Resonance Spectroscopy Mass Spectrometry Medical sciences Micromonospora - metabolism Micromonospora griseorubida Pharmacology. Drug treatments Spectrometry, Mass, Fast Atom Bombardment Spectrophotometry, Infrared Spectrophotometry, Ultraviolet
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Zusammenfassung:	Novel 16-membered macrolide antibiotics, mycinamicins IX, XII, XIII, XIV, XV, XVI, XVII and XVIII have been isolated from the culture filtrate of Micromonospora griseorubida (FERM BP-705). Fermentation, isolation, structure determination and biosynthetic consideration of these mycinamicin analogs are described.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.45.1