Glomerulonephritis with end-stage liver disease in childhood

Renal biopsies were done perioperatively in 18 children receiving liver grafts. All specimens showed glomerulonephritis, which was mesangialproliferative in 15 and mesangio-capillary in 3. Of the 16 children who were alive four or more months after transplantation, only 1 showed progressive deterior...

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Veröffentlicht in:	The Lancet (British edition) 1992-03, Vol.339 (8795), p.706-707
Hauptverfasser:	Noble-Jamieson, G., Thiru, S., Johnston, P., Friend, P., Barnes, N.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Biological and medical sciences Child Child, Preschool Children & youth Disease Glomerulonephritis, Membranoproliferative - complications Humans Infant Kidneys Liver Liver Diseases - complications Liver Diseases - surgery Liver Transplantation Liver, biliary tract, pancreas, portal circulation, spleen Medical research Medical sciences Postoperative Complications Renal function Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system Transplants & implants
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Beschreibung
Zusammenfassung:	Renal biopsies were done perioperatively in 18 children receiving liver grafts. All specimens showed glomerulonephritis, which was mesangialproliferative in 15 and mesangio-capillary in 3. Of the 16 children who were alive four or more months after transplantation, only 1 showed progressive deterioration of renal function; 1 other had a subnormal but static glomerular filtration rate. In all 6 children who had proteinuria before operation, the urine became normal.
ISSN:	0140-6736 1474-547X
DOI:	10.1016/0140-6736(92)90600-8