Fulminant peptic ulcer disease in cardiac surgical patients: Pathogenesis, prevention, and management

OBJECTIVESTo identify pathogenetic factors associated with the development of peptic ulcers in patients following cardiac surgery and to examine the efficacy of medical and surgical therapy of peptic ulcers in this setting. DESIGNRetrospective study with randomly selected case controls. SETTINGUnive...

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Veröffentlicht in:	Critical care medicine 1992-03, Vol.20 (3), p.354-359
Hauptverfasser:	ROSEN, HAROLD R, VLAHAKES, GUS J, RATTNER, DAVID W
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anesthesia Anesthesia depending on type of surgery Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anti-Ulcer Agents - therapeutic use Biological and medical sciences Blood Transfusion Cardiac Surgical Procedures Cause of Death Female Gastrointestinal Hemorrhage - drug therapy Histamine H2 Antagonists - therapeutic use Humans Intensive Care Units Male Medical sciences Middle Aged Peptic Ulcer - etiology Peptic Ulcer - prevention & control Peptic Ulcer - therapy Postoperative Complications - etiology Postoperative Complications - prevention & control Postoperative Complications - therapy Retrospective Studies Risk Factors Stress, Physiological - complications Thoracic and cardiovascular surgery. Cardiopulmonary bypass
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Zusammenfassung:	OBJECTIVESTo identify pathogenetic factors associated with the development of peptic ulcers in patients following cardiac surgery and to examine the efficacy of medical and surgical therapy of peptic ulcers in this setting. DESIGNRetrospective study with randomly selected case controls. SETTINGUniversity hospital referral practice. PATIENTSA total of 9,199 consecutive patients undergoing procedures requiring cardiopulmonary bypass between January 1, 1980 through September 30, 1988, were reviewed. Life-threatening ulcer complications were defined as hemorrhage of
ISSN:	0090-3493 1530-0293
DOI:	10.1097/00003246-199203000-00011