Anomalous ABO Phenotype in a Child after an ABO-Incompatible Liver Transplantation

RED-CELL A and B antigens are primarily intrinsic membrane glycoproteins that become attached during erythropoiesis by specific A and B transferase enzymes. 1 A and B antigens may also be acquired by red-cell adsorption of A and B substances present in the plasma of secretors. 2 The acquisition or l...

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Veröffentlicht in:The New England journal of medicine 1992-03, Vol.326 (13), p.867-870
Hauptverfasser: Comenzo, Raymond L, Malachowski, Marie E, Rohrer, Richard J, Freeman, Richard B, Rabson, Arthur, Berkman, Eugene M
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Sprache:eng
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Zusammenfassung:RED-CELL A and B antigens are primarily intrinsic membrane glycoproteins that become attached during erythropoiesis by specific A and B transferase enzymes. 1 A and B antigens may also be acquired by red-cell adsorption of A and B substances present in the plasma of secretors. 2 The acquisition or loss of ABO antigens has been reported in association with cancers, hematologic disorders, infections, and bone marrow transplantation. 3 Except in emergencies, the compatibility of the donor's and the recipient's ABO blood types is ensured in liver transplantation. 4 5 6 In this report we describe a successful ABO-incompatible liver transplantation in a child whose blood type . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM199203263261305