Lack of resolution of ectopic pregnancy by intratubal injection of methotrexate

Although reports of local injection of MTX in the treatment of EP appeared to be promising, our results do not confirm the efficacy of this approach. Our experience was sufficiently discouraging to prompt discontinuation of a randomized trail; our hope is that others will add to the accumulating dat...

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Veröffentlicht in:	Fertility and sterility 1992-03, Vol.57 (3), p.685-687
Hauptverfasser:	Mottla, Gilbert L., Rulin, Marvin C., Guzick, David S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Induced Biological and medical sciences Chorionic Gonadotropin - administration & dosage Chorionic Gonadotropin - therapeutic use Ectopic pregnancy Fallopian Tubes Female Genital system. Reproduction Humans Injections Injections, Intramuscular Laparoscopy Medical sciences methotrexate Methotrexate - administration & dosage Methotrexate - therapeutic use Pharmacology. Drug treatments Pregnancy Pregnancy, Ectopic - surgery Salpingostomy
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Beschreibung
Zusammenfassung:	Although reports of local injection of MTX in the treatment of EP appeared to be promising, our results do not confirm the efficacy of this approach. Our experience was sufficiently discouraging to prompt discontinuation of a randomized trail; our hope is that others will add to the accumulating data base so that the role of local injection of MTX can be clarified.
ISSN:	0015-0282 1556-5653
DOI:	10.1016/S0015-0282(16)54922-X