Brosimacutins A−I, Nine New Flavonoids from Brosimum acutifolium

Brosimacutins A−I, Nine New Flavonoids from Brosimum acutifolium

Nine new flavonoids, brosimacutins A-I (1-9), and four known flavonoids were isolated from the bark of Brosimum acutifolium, a Brazilian folk medicine ("Mururé"). Their structures were elucidated by spectroscopic methods, including 2D NMR. Brosimacutins A-I possess differentially functiona...

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Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 2002-12, Vol.65 (12), p.1843-1847
Hauptverfasser: TAKASHIMA, Junko, OHSAKI, Ayumi
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Brazil
Flavonoids - chemistry
Flavonoids - isolation & purification
General pharmacology
Medical sciences
Medicine, Traditional
Molecular Conformation
Molecular Structure
Moraceae - chemistry
Nuclear Magnetic Resonance, Biomolecular
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plants, Medicinal - chemistry
Structure-Activity Relationship
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Zusammenfassung:Nine new flavonoids, brosimacutins A-I (1-9), and four known flavonoids were isolated from the bark of Brosimum acutifolium, a Brazilian folk medicine ("Mururé"). Their structures were elucidated by spectroscopic methods, including 2D NMR. Brosimacutins A-I possess differentially functionalized isoprene units at C-8.
ISSN:0163-3864
1520-6025
DOI:10.1021/np020241f