Isotopically labeled analogues for drug quantitation

Liu et al look at how to overcome problems associated with using isotopically labeled analogues as internal standards for the quantitation of drugs in media. If analytical instrumentation and specimen pretreatment technologies are the "hardware" aspects of the analytical sciences, then ILA...

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Veröffentlicht in:Analytical chemistry (Washington) 2002-12, Vol.74 (23), p.618A-626A
Hauptverfasser: LIU, Ray H, LIN, D.-L, CHANG, Wei-Tung, CHIAREIY LIU, TSAY, Wen-Ing, LI, Jih-Heng, KUO, Tsung-Li
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container_end_page 626A
container_issue 23
container_start_page 618A
container_title Analytical chemistry (Washington)
container_volume 74
creator LIU, Ray H
LIN, D.-L
CHANG, Wei-Tung
CHIAREIY LIU
TSAY, Wen-Ing
LI, Jih-Heng
KUO, Tsung-Li
description Liu et al look at how to overcome problems associated with using isotopically labeled analogues as internal standards for the quantitation of drugs in media. If analytical instrumentation and specimen pretreatment technologies are the "hardware" aspects of the analytical sciences, then ILAs may be considered the complementary "software" component that is needed for advanced hardware to reach its full potential in quantitation.
doi_str_mv 10.1021/ac022161m
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source ACS Publications; MEDLINE
subjects Analysis
Analytical chemistry
Biological and medical sciences
Chemistry
Chromatographic methods and physical methods associated with chromatography
Drug Monitoring - methods
Drug Monitoring - standards
Drugs
Exact sciences and technology
Gas chromatographic methods
General pharmacology
Isotopes
Isotopes - standards
Mass Spectrometry
Medical sciences
Pharmaceutical Preparations - analysis
Pharmacology. Drug treatments
Reference Standards
Spectrometric and optical methods
title Isotopically labeled analogues for drug quantitation
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