The Na+/Ca2+ exchange molecule: an overview
An overview of the molecular physiology of the Na(+)/Ca(2+) exchanger is presented. This includes information on the variety of exchangers that have been described and their regulatory properties. Molecular insight is most detailed for the cardiac Na(+)/Ca(2+) exchanger (NCX1). Parts of the NCS1 mol...
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| Veröffentlicht in: | Annals of the New York Academy of Sciences 2002-11, Vol.976, p.1-10 |
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| container_title | Annals of the New York Academy of Sciences |
| container_volume | 976 |
| creator | Philipson, Kenneth D Nicoll, Debora A Ottolia, Michela Quednau, Beate D Reuter, Hannes John, Scott Qiu, Zhiyong |
| description | An overview of the molecular physiology of the Na(+)/Ca(2+) exchanger is presented. This includes information on the variety of exchangers that have been described and their regulatory properties. Molecular insight is most detailed for the cardiac Na(+)/Ca(2+) exchanger (NCX1). Parts of the NCS1 molecule involved in regulation and ion transport have been elucidated, and initial information on the topology and structure is available. |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0077-8923 |
| ispartof | Annals of the New York Academy of Sciences, 2002-11, Vol.976, p.1-10 |
| issn | 0077-8923 |
| language | eng |
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| source | MEDLINE; Wiley Journals |
| subjects | Alternative Splicing Animals Brain - physiology Heart - physiology Kidney - physiology Models, Molecular Organ Specificity Protein Conformation Sodium-Calcium Exchanger - chemistry Sodium-Calcium Exchanger - genetics Sodium-Calcium Exchanger - physiology |
| title | The Na+/Ca2+ exchange molecule: an overview |
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