Occurrence of Bronchioloalveolar Cell Carcinoma in Two Brothers: Comparison of Clinical Features and Immunohistochemical Findings
It has been suggested that lung cancer sometimes aggregates in families. However, the familial occurrence of bronchioloalveolar carcinoma (BAC) is extremely rare. We present a family in which two brothers had BAC. The clinical features and immunohistochemical findings of BAC in the two brothers were...
Gespeichert in:
| Veröffentlicht in: | Internal Medicine 2002, Vol.41(11), pp.1002-1006 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1006 |
|---|---|
| container_issue | 11 |
| container_start_page | 1002 |
| container_title | Internal Medicine |
| container_volume | 41 |
| creator | NANKI, Nobuki FUJITA, Jiro OHTSUKI, Yuji BANDOH, Shuji OHARA, Nobuya MIYATANI, Katsuya YAMAJI, Yasufumi ISHIDA, Toshihiko |
| description | It has been suggested that lung cancer sometimes aggregates in families. However, the familial occurrence of bronchioloalveolar carcinoma (BAC) is extremely rare. We present a family in which two brothers had BAC. The clinical features and immunohistochemical findings of BAC in the two brothers were compared. Immunohistochemical findings revealed that both cases of BAC had very similar immunopathological features in epithelial marker expression. A review of the literature revealed that this is the third case of BACs in a single family. (Internal Medicine 41:1002-1006, 2002) |
| doi_str_mv | 10.2169/internalmedicine.41.1002 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72784176</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72784176</sourcerecordid><originalsourceid>FETCH-LOGICAL-c491t-bbddf3a02e3bbb3d791b7fd3fa24d1454a9640cb6cd9d9325ffc58270033c6283</originalsourceid><addsrcrecordid>eNplkE1v1DAQhi0EokvhLyBf4JYl_kgcc4OIlkqVeqCco4k96bpy7MVOQBz55yTdqJXgMj74mZl3HkIoK_ec1fqDCxOmAH5E64wLuJdsz8qSPyM7JqQuFBfVc7IrNWsKvpQz8irn-7IUjdL8JTljXDaKqWZH_twYM6eEwSCNA_2cYjAHF30E_xOjh0Rb9J62kJY9cQTqAr39FVdwOmDKH2kbxyMkl2NYB7TeBWfA0wuEaU6YKQRLr8ZxDvHg8hTNAccT4IJ14S6_Ji8G8BnfbO85-X7x5bb9WlzfXF61n64LIzWbir63dhBQchR93wurNOvVYMUAXFomKwm6lqXpa2O11YJXw2CqhqvlaGFq3ohz8v4095jijxnz1I0um-U4CBjn3CmuGslUvYDNCTQp5pxw6I7JjZB-d6zsVv3dv_o7ybpV_9L6dtsx98vnU-PmewHebQDkRcKQIBiXnzgpa1VVK_ftxN3nCe7wEYA0OePxvwRMa_6Qgm11jfNImwOkDoP4C8VutEY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72784176</pqid></control><display><type>article</type><title>Occurrence of Bronchioloalveolar Cell Carcinoma in Two Brothers: Comparison of Clinical Features and Immunohistochemical Findings</title><source>J-STAGE Free</source><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>NANKI, Nobuki ; FUJITA, Jiro ; OHTSUKI, Yuji ; BANDOH, Shuji ; OHARA, Nobuya ; MIYATANI, Katsuya ; YAMAJI, Yasufumi ; ISHIDA, Toshihiko</creator><creatorcontrib>NANKI, Nobuki ; FUJITA, Jiro ; OHTSUKI, Yuji ; BANDOH, Shuji ; OHARA, Nobuya ; MIYATANI, Katsuya ; YAMAJI, Yasufumi ; ISHIDA, Toshihiko</creatorcontrib><description>It has been suggested that lung cancer sometimes aggregates in families. However, the familial occurrence of bronchioloalveolar carcinoma (BAC) is extremely rare. We present a family in which two brothers had BAC. The clinical features and immunohistochemical findings of BAC in the two brothers were compared. Immunohistochemical findings revealed that both cases of BAC had very similar immunopathological features in epithelial marker expression. A review of the literature revealed that this is the third case of BACs in a single family. (Internal Medicine 41:1002-1006, 2002)</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.41.1002</identifier><identifier>PMID: 12487178</identifier><language>eng</language><publisher>Tokyo: The Japanese Society of Internal Medicine</publisher><subject>Adenocarcinoma, Bronchiolo-Alveolar - genetics ; Adenocarcinoma, Bronchiolo-Alveolar - pathology ; Biological and medical sciences ; bronchioloalveolar carcinoma ; family ; Humans ; Immunohistochemistry ; Investigative techniques, diagnostic techniques (general aspects) ; Lung Neoplasms - genetics ; Lung Neoplasms - pathology ; Male ; Medical sciences ; Middle Aged ; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques ; Pedigree ; Respiratory system</subject><ispartof>Internal Medicine, 2002, Vol.41(11), pp.1002-1006</ispartof><rights>The Japanese Society of Internal Medicine</rights><rights>2003 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1881,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14467558$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12487178$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>NANKI, Nobuki</creatorcontrib><creatorcontrib>FUJITA, Jiro</creatorcontrib><creatorcontrib>OHTSUKI, Yuji</creatorcontrib><creatorcontrib>BANDOH, Shuji</creatorcontrib><creatorcontrib>OHARA, Nobuya</creatorcontrib><creatorcontrib>MIYATANI, Katsuya</creatorcontrib><creatorcontrib>YAMAJI, Yasufumi</creatorcontrib><creatorcontrib>ISHIDA, Toshihiko</creatorcontrib><title>Occurrence of Bronchioloalveolar Cell Carcinoma in Two Brothers: Comparison of Clinical Features and Immunohistochemical Findings</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>It has been suggested that lung cancer sometimes aggregates in families. However, the familial occurrence of bronchioloalveolar carcinoma (BAC) is extremely rare. We present a family in which two brothers had BAC. The clinical features and immunohistochemical findings of BAC in the two brothers were compared. Immunohistochemical findings revealed that both cases of BAC had very similar immunopathological features in epithelial marker expression. A review of the literature revealed that this is the third case of BACs in a single family. (Internal Medicine 41:1002-1006, 2002)</description><subject>Adenocarcinoma, Bronchiolo-Alveolar - genetics</subject><subject>Adenocarcinoma, Bronchiolo-Alveolar - pathology</subject><subject>Biological and medical sciences</subject><subject>bronchioloalveolar carcinoma</subject><subject>family</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Lung Neoplasms - genetics</subject><subject>Lung Neoplasms - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</subject><subject>Pedigree</subject><subject>Respiratory system</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkE1v1DAQhi0EokvhLyBf4JYl_kgcc4OIlkqVeqCco4k96bpy7MVOQBz55yTdqJXgMj74mZl3HkIoK_ec1fqDCxOmAH5E64wLuJdsz8qSPyM7JqQuFBfVc7IrNWsKvpQz8irn-7IUjdL8JTljXDaKqWZH_twYM6eEwSCNA_2cYjAHF30E_xOjh0Rb9J62kJY9cQTqAr39FVdwOmDKH2kbxyMkl2NYB7TeBWfA0wuEaU6YKQRLr8ZxDvHg8hTNAccT4IJ14S6_Ji8G8BnfbO85-X7x5bb9WlzfXF61n64LIzWbir63dhBQchR93wurNOvVYMUAXFomKwm6lqXpa2O11YJXw2CqhqvlaGFq3ohz8v4095jijxnz1I0um-U4CBjn3CmuGslUvYDNCTQp5pxw6I7JjZB-d6zsVv3dv_o7ybpV_9L6dtsx98vnU-PmewHebQDkRcKQIBiXnzgpa1VVK_ftxN3nCe7wEYA0OePxvwRMa_6Qgm11jfNImwOkDoP4C8VutEY</recordid><startdate>20021101</startdate><enddate>20021101</enddate><creator>NANKI, Nobuki</creator><creator>FUJITA, Jiro</creator><creator>OHTSUKI, Yuji</creator><creator>BANDOH, Shuji</creator><creator>OHARA, Nobuya</creator><creator>MIYATANI, Katsuya</creator><creator>YAMAJI, Yasufumi</creator><creator>ISHIDA, Toshihiko</creator><general>The Japanese Society of Internal Medicine</general><general>Japanese Society of Internal Medicine</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20021101</creationdate><title>Occurrence of Bronchioloalveolar Cell Carcinoma in Two Brothers: Comparison of Clinical Features and Immunohistochemical Findings</title><author>NANKI, Nobuki ; FUJITA, Jiro ; OHTSUKI, Yuji ; BANDOH, Shuji ; OHARA, Nobuya ; MIYATANI, Katsuya ; YAMAJI, Yasufumi ; ISHIDA, Toshihiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c491t-bbddf3a02e3bbb3d791b7fd3fa24d1454a9640cb6cd9d9325ffc58270033c6283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adenocarcinoma, Bronchiolo-Alveolar - genetics</topic><topic>Adenocarcinoma, Bronchiolo-Alveolar - pathology</topic><topic>Biological and medical sciences</topic><topic>bronchioloalveolar carcinoma</topic><topic>family</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Lung Neoplasms - genetics</topic><topic>Lung Neoplasms - pathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</topic><topic>Pedigree</topic><topic>Respiratory system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>NANKI, Nobuki</creatorcontrib><creatorcontrib>FUJITA, Jiro</creatorcontrib><creatorcontrib>OHTSUKI, Yuji</creatorcontrib><creatorcontrib>BANDOH, Shuji</creatorcontrib><creatorcontrib>OHARA, Nobuya</creatorcontrib><creatorcontrib>MIYATANI, Katsuya</creatorcontrib><creatorcontrib>YAMAJI, Yasufumi</creatorcontrib><creatorcontrib>ISHIDA, Toshihiko</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>NANKI, Nobuki</au><au>FUJITA, Jiro</au><au>OHTSUKI, Yuji</au><au>BANDOH, Shuji</au><au>OHARA, Nobuya</au><au>MIYATANI, Katsuya</au><au>YAMAJI, Yasufumi</au><au>ISHIDA, Toshihiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Occurrence of Bronchioloalveolar Cell Carcinoma in Two Brothers: Comparison of Clinical Features and Immunohistochemical Findings</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2002-11-01</date><risdate>2002</risdate><volume>41</volume><issue>11</issue><spage>1002</spage><epage>1006</epage><pages>1002-1006</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>It has been suggested that lung cancer sometimes aggregates in families. However, the familial occurrence of bronchioloalveolar carcinoma (BAC) is extremely rare. We present a family in which two brothers had BAC. The clinical features and immunohistochemical findings of BAC in the two brothers were compared. Immunohistochemical findings revealed that both cases of BAC had very similar immunopathological features in epithelial marker expression. A review of the literature revealed that this is the third case of BACs in a single family. (Internal Medicine 41:1002-1006, 2002)</abstract><cop>Tokyo</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>12487178</pmid><doi>10.2169/internalmedicine.41.1002</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0918-2918 |
| ispartof | Internal Medicine, 2002, Vol.41(11), pp.1002-1006 |
| issn | 0918-2918 1349-7235 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_72784176 |
| source | J-STAGE Free; MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adenocarcinoma, Bronchiolo-Alveolar - genetics Adenocarcinoma, Bronchiolo-Alveolar - pathology Biological and medical sciences bronchioloalveolar carcinoma family Humans Immunohistochemistry Investigative techniques, diagnostic techniques (general aspects) Lung Neoplasms - genetics Lung Neoplasms - pathology Male Medical sciences Middle Aged Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Pedigree Respiratory system |
| title | Occurrence of Bronchioloalveolar Cell Carcinoma in Two Brothers: Comparison of Clinical Features and Immunohistochemical Findings |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T10%3A57%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Occurrence%20of%20Bronchioloalveolar%20Cell%20Carcinoma%20in%20Two%20Brothers:%20Comparison%20of%20Clinical%20Features%20and%20Immunohistochemical%20Findings&rft.jtitle=Internal%20Medicine&rft.au=NANKI,%20Nobuki&rft.date=2002-11-01&rft.volume=41&rft.issue=11&rft.spage=1002&rft.epage=1006&rft.pages=1002-1006&rft.issn=0918-2918&rft.eissn=1349-7235&rft_id=info:doi/10.2169/internalmedicine.41.1002&rft_dat=%3Cproquest_cross%3E72784176%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=72784176&rft_id=info:pmid/12487178&rfr_iscdi=true |