Sarcoid granuloma simulating amelanotic melanoma of the iris: a case report

We report the case of a unilateral vascular iris tumor in a 24-year-old patient. Clinically, the iris lesion appeared similar to amelanotic melanoma. A systemic work-up (initial check-up), including an angiotensin-converting enzyme determination, provided the diagnosis of sarcoid granuloma. A biopsy...

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Veröffentlicht in:	Journal français d'ophtalmologie 2002-10, Vol.25 (8), p.831-834
Hauptverfasser:	Rouberol, F, Duquesne, N, Kodjikian, L, Guerillon, F, Grange, J D
Format:	Artikel
Sprache:	fre
Schlagworte:	Administration, Topical Adrenal Cortex Hormones - administration & dosage Adrenal Cortex Hormones - therapeutic use Adult Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - therapeutic use Dexamethasone - administration & dosage Dexamethasone - therapeutic use Diagnosis, Differential Follow-Up Studies Glucocorticoids Granuloma - diagnosis Granuloma - drug therapy Humans Iris Diseases - diagnosis Iris Diseases - drug therapy Iris Neoplasms - diagnosis Male Melanoma, Amelanotic - diagnosis Neomycin - administration & dosage Neomycin - therapeutic use Sarcoidosis - diagnosis Sarcoidosis - drug therapy Time Factors Visual Acuity
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Zusammenfassung:	We report the case of a unilateral vascular iris tumor in a 24-year-old patient. Clinically, the iris lesion appeared similar to amelanotic melanoma. A systemic work-up (initial check-up), including an angiotensin-converting enzyme determination, provided the diagnosis of sarcoid granuloma. A biopsy confirmation was not needed. We concluded that iris granuloma can be the only ocular manifestation of sarcoidosis and this context is likely to be confused with amelanotic melanoma and metastatic carcinoma.
ISSN:	0181-5512