Chromosome structure and eukaryotic gene organization

The DNA in the eukaryotic nucleus is highly compacted but well organized into distinct regional units. Chromosomal bands are characterized by their structure and distinctive replication time. They are subdivided into chromatin loops which serve as functional domains that have discrete boundary eleme...

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Veröffentlicht in:	Current opinion in genetics & development 1991-12, Vol.1 (4), p.534-537
Hauptverfasser:	Kitsberg, Daniel, Selig, Sara, Cedar, Howard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chickens - genetics Chromatin - ultrastructure Chromosomes - ultrastructure DNA - genetics Drosophila - genetics Gene Expression Regulation Mammals - genetics Regulatory Sequences, Nucleic Acid
Online-Zugang:	Volltext
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Zusammenfassung:	The DNA in the eukaryotic nucleus is highly compacted but well organized into distinct regional units. Chromosomal bands are characterized by their structure and distinctive replication time. They are subdivided into chromatin loops which serve as functional domains that have discrete boundary elements and can be regulated during development.
ISSN:	0959-437X 1879-0380
DOI:	10.1016/S0959-437X(05)80204-7