Microfilaments and microtubules: the news from yeast

New evidence that cortical actin patches and the endocytic machinery share components supports the idea that actin patches are in fact transient membrane coats at the initial stage of endocytosis. Recent studies of actin cables have identified formins as the core of a novel actin-filament-assembling...

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Veröffentlicht in:Current Opinion in Microbiology 2002-12, Vol.5 (6), p.564-574
Hauptverfasser: Schott, Daniel, Huffaker, Tim, Bretscher, Anthony
Format: Artikel
Sprache:eng
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Zusammenfassung:New evidence that cortical actin patches and the endocytic machinery share components supports the idea that actin patches are in fact transient membrane coats at the initial stage of endocytosis. Recent studies of actin cables have identified formins as the core of a novel actin-filament-assembling machine. Meanwhile, microtubule-binding proteins have been found in the kinetochore, and factors affecting microtubule dynamic instability have been identified. Recent discoveries in yeast include a conserved microfilament assembly machine, new hints that initial endocytic membranes bear dense but fleeting actin coats, and molecular connections between kinetochores and microtubules.
ISSN:1369-5274
1879-0364
DOI:10.1016/S1369-5274(02)00369-7