Cross-jurisdictional transmission of Mycobacterium tuberculosis in Maryland and Washington, D C, 1996-2000, linked to the homeless

From 1996 to 2000, 23 Maryland and Washington, D.C., tuberculosis cases were identified in one six-band DNA cluster. Cases were clustered on the basis of their Mycobacterium tuberculosis isolates. Medical record reviews and interviews were conducted to identify epidemiologic linkages. Eighteen (78%)...

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Veröffentlicht in:	Emerging infectious diseases 2002-11, Vol.8 (11), p.1249-1251
Hauptverfasser:	Lathan, Monica, Mukasa, Leonard Ntaate, Hooper, Nancy, Golub, Jonathan, Baruch, Nancy, Mulcahy, Donna, Benjamin, William, Cronin, Wendy A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cluster Analysis Disease Outbreaks District of Columbia - epidemiology Female Genotype Homeless Persons Humans Male Maryland - epidemiology Middle Aged Molecular Epidemiology Mycobacterium tuberculosis - classification Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - isolation & purification Polymorphism, Restriction Fragment Length Risk Factors Time Factors Tuberculosis - epidemiology Tuberculosis - microbiology Tuberculosis - transmission
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Beschreibung
Zusammenfassung:	From 1996 to 2000, 23 Maryland and Washington, D.C., tuberculosis cases were identified in one six-band DNA cluster. Cases were clustered on the basis of their Mycobacterium tuberculosis isolates. Medical record reviews and interviews were conducted to identify epidemiologic linkages. Eighteen (78%) of the 23 case-patients with identical restriction fragment length polymorphism patterns were linked to another member; half the patients were associated with a Washington, D.C., homeless shelter. Molecular epidemiology defined the extent of this large, cross-jurisdictional outbreak.
ISSN:	1080-6040