Free Radical-Mediated Vinyl Amination: Access to N,N-Dialkyl Enamines and Their β-Stannyl and β-Thio Derivatives

The first examples of free radical-mediated vinyl amination are described by nonconventional vinyl radical addition to azomethine nitrogen. This new vinyl amination protocol is mild and provides convenient synthetic access to nonstabilized N,N-dialkyl enamines and tandem bond-forming processes.

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Bibliographische Detailangaben
Veröffentlicht in:	Organic letters 2002-11, Vol.4 (24), p.4197-4200
Hauptverfasser:	Prabhakaran, Erode N, Nugent, Benjamin M, Williams, Amie L, Nailor, Kristen E, Johnston, Jeffrey N
Format:	Artikel
Sprache:	eng
Schlagworte:	Amination Free Radicals - chemistry Heterocyclic Compounds - chemistry Magnetic Resonance Spectroscopy Molecular Structure
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The first examples of free radical-mediated vinyl amination are described by nonconventional vinyl radical addition to azomethine nitrogen. This new vinyl amination protocol is mild and provides convenient synthetic access to nonstabilized N,N-dialkyl enamines and tandem bond-forming processes.
ISSN:	1523-7060 1523-7052
DOI:	10.1021/ol027064u