Chemical modification of a viral cage for multivalent presentation

Chemical modification of a viral cage for multivalent presentation

Here we present generalized methods for chemically modifying the surface of a viral protein cage; this exploits the chemistry of native and engineered surface exposed functional groups for multivalent presentation of ligands.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2002-10 (20), p.2390-2391
Hauptverfasser: Gillitzer, Eric, Willits, Debbie, Young, Mark, Douglas, Trevor
Format: Artikel
Sprache:eng
Schlagworte:
Bromovirus - chemistry
Crystallization
Fluorescent Dyes
Ligands
Models, Molecular
Peptides - chemistry
Protein Engineering - methods
Surface Properties
Viral Proteins - chemistry
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Here we present generalized methods for chemically modifying the surface of a viral protein cage; this exploits the chemistry of native and engineered surface exposed functional groups for multivalent presentation of ligands.
ISSN:1359-7345
1364-548X
DOI:10.1039/b207853h