How To Get the Most Out of Two Phosphorus Chemistries. Studies on H-Phosphonates

How To Get the Most Out of Two Phosphorus Chemistries. Studies on H-Phosphonates

The biological importance and practical significance of phosphate esters and their analogues have been the major driving forces for research in various areas of synthetic organic phosphorus chemistry. In this Account, the authors' studies on the development of a comprehensive H-phosphonate meth...

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Veröffentlicht in:Accounts of chemical research 2002-11, Vol.35 (11), p.952-960
Hauptverfasser: Stawinski, Jacek, Kraszewski, Adam
Format: Artikel
Sprache:eng
Schlagworte:
Oligonucleotides - chemical synthesis
Oligonucleotides - chemistry
Organophosphonates - chemistry
Oxidation-Reduction
Phosphites - chemistry
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Zusammenfassung:The biological importance and practical significance of phosphate esters and their analogues have been the major driving forces for research in various areas of synthetic organic phosphorus chemistry. In this Account, the authors' studies on the development of a comprehensive H-phosphonate methodology and the underlying chemistry for the preparation of biologically important phosphate esters and their analogues are briefly discussed.
ISSN:0001-4842
1520-4898
DOI:10.1021/ar010049p