Calcium transport proteins in active secretory zones: Na-Ca exchange isoforms and exchanger kinetic properties in chromaffin granules and plasma membranes

We have found that Na-Ca exchange influences Ca(2+) efflux, signal decay, and the rate of secretion in chromaffin cells. We now report the presence of two distinct splicing variant isoforms of Na-Ca exchange proteins in bovine chromaffin cells and their transport properties in chromaffin granules an...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Annals of the New York Academy of Sciences 2002-10, Vol.971 (1), p.142-144
Hauptverfasser: Schneider, A S, Mah, S J, Farhadi, M, Grindi, E, Davis, K H
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 144
container_issue 1
container_start_page 142
container_title Annals of the New York Academy of Sciences
container_volume 971
creator Schneider, A S
Mah, S J
Farhadi, M
Grindi, E
Davis, K H
description We have found that Na-Ca exchange influences Ca(2+) efflux, signal decay, and the rate of secretion in chromaffin cells. We now report the presence of two distinct splicing variant isoforms of Na-Ca exchange proteins in bovine chromaffin cells and their transport properties in chromaffin granules and plasma membrane vesicles.
doi_str_mv 10.1111/j.1749-6632.2002.tb04449.x
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72685902</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72685902</sourcerecordid><originalsourceid>FETCH-LOGICAL-c258t-2680683b89daf60242a533f5856f5f0f48054419455143fcd9dc86a5001b69f73</originalsourceid><addsrcrecordid>eNpFUU1v1DAQtRCIbgt_AVkcuCX4M3F6QyugSBVc4Gw5zrj1EifBdqotP4Vfi8Ouylw8Gs97b_QeQm8pqWmp94eatqKrmoazmhHC6twTIURXH5-h3dPXc7QjpG0r1TF-gS5TOhBCmRLtS3RBmeCKErlDf_ZmtH4NOEczpWWOGS9xzuCnhP2Ejc3-AXACGyHP8RH_nidI1_irqfYGw9Hem-kOsE-zm2NI2EzD0zTin36C7O3GuEDMHv5x2vs4B-Ncae-K6DrCCbeMJgWDA4S-jCG9Qi-cGRO8Pr9X6Menj9_3N9Xtt89f9h9uK8ukyhVrFGkU71U3GNcQJpiRnDupZOOkI04oIoWgnZCSCu7s0A1WNUYWN_qmcy2_Qu9OvOXMXyukrINPFsaxHDGvSbdFQXaElcXr06KNc0oRnF6iDyY-akr0low-6M1-vdmvt2T0ORl9LOA3Z5W1DzD8h56j4H8BrbCOXg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72685902</pqid></control><display><type>article</type><title>Calcium transport proteins in active secretory zones: Na-Ca exchange isoforms and exchanger kinetic properties in chromaffin granules and plasma membranes</title><source>MEDLINE</source><source>Wiley Online Library All Journals</source><creator>Schneider, A S ; Mah, S J ; Farhadi, M ; Grindi, E ; Davis, K H</creator><creatorcontrib>Schneider, A S ; Mah, S J ; Farhadi, M ; Grindi, E ; Davis, K H</creatorcontrib><description>We have found that Na-Ca exchange influences Ca(2+) efflux, signal decay, and the rate of secretion in chromaffin cells. We now report the presence of two distinct splicing variant isoforms of Na-Ca exchange proteins in bovine chromaffin cells and their transport properties in chromaffin granules and plasma membrane vesicles.</description><identifier>ISSN: 0077-8923</identifier><identifier>EISSN: 1749-6632</identifier><identifier>DOI: 10.1111/j.1749-6632.2002.tb04449.x</identifier><identifier>PMID: 12438105</identifier><language>eng</language><publisher>United States</publisher><subject>Alternative Splicing ; Amino Acid Sequence ; Animals ; Biological Transport ; Calcium - metabolism ; Cattle ; Cell Membrane - metabolism ; Chromaffin Cells - metabolism ; Exons ; Kinetics ; Molecular Sequence Data ; Myocardium - metabolism ; Protein Isoforms ; Sequence Homology, Amino Acid ; Sodium-Calcium Exchanger - chemistry</subject><ispartof>Annals of the New York Academy of Sciences, 2002-10, Vol.971 (1), p.142-144</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c258t-2680683b89daf60242a533f5856f5f0f48054419455143fcd9dc86a5001b69f73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12438105$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schneider, A S</creatorcontrib><creatorcontrib>Mah, S J</creatorcontrib><creatorcontrib>Farhadi, M</creatorcontrib><creatorcontrib>Grindi, E</creatorcontrib><creatorcontrib>Davis, K H</creatorcontrib><title>Calcium transport proteins in active secretory zones: Na-Ca exchange isoforms and exchanger kinetic properties in chromaffin granules and plasma membranes</title><title>Annals of the New York Academy of Sciences</title><addtitle>Ann N Y Acad Sci</addtitle><description>We have found that Na-Ca exchange influences Ca(2+) efflux, signal decay, and the rate of secretion in chromaffin cells. We now report the presence of two distinct splicing variant isoforms of Na-Ca exchange proteins in bovine chromaffin cells and their transport properties in chromaffin granules and plasma membrane vesicles.</description><subject>Alternative Splicing</subject><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Biological Transport</subject><subject>Calcium - metabolism</subject><subject>Cattle</subject><subject>Cell Membrane - metabolism</subject><subject>Chromaffin Cells - metabolism</subject><subject>Exons</subject><subject>Kinetics</subject><subject>Molecular Sequence Data</subject><subject>Myocardium - metabolism</subject><subject>Protein Isoforms</subject><subject>Sequence Homology, Amino Acid</subject><subject>Sodium-Calcium Exchanger - chemistry</subject><issn>0077-8923</issn><issn>1749-6632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFUU1v1DAQtRCIbgt_AVkcuCX4M3F6QyugSBVc4Gw5zrj1EifBdqotP4Vfi8Ouylw8Gs97b_QeQm8pqWmp94eatqKrmoazmhHC6twTIURXH5-h3dPXc7QjpG0r1TF-gS5TOhBCmRLtS3RBmeCKErlDf_ZmtH4NOEczpWWOGS9xzuCnhP2Ejc3-AXACGyHP8RH_nidI1_irqfYGw9Hem-kOsE-zm2NI2EzD0zTin36C7O3GuEDMHv5x2vs4B-Ncae-K6DrCCbeMJgWDA4S-jCG9Qi-cGRO8Pr9X6Menj9_3N9Xtt89f9h9uK8ukyhVrFGkU71U3GNcQJpiRnDupZOOkI04oIoWgnZCSCu7s0A1WNUYWN_qmcy2_Qu9OvOXMXyukrINPFsaxHDGvSbdFQXaElcXr06KNc0oRnF6iDyY-akr0low-6M1-vdmvt2T0ORl9LOA3Z5W1DzD8h56j4H8BrbCOXg</recordid><startdate>200210</startdate><enddate>200210</enddate><creator>Schneider, A S</creator><creator>Mah, S J</creator><creator>Farhadi, M</creator><creator>Grindi, E</creator><creator>Davis, K H</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200210</creationdate><title>Calcium transport proteins in active secretory zones: Na-Ca exchange isoforms and exchanger kinetic properties in chromaffin granules and plasma membranes</title><author>Schneider, A S ; Mah, S J ; Farhadi, M ; Grindi, E ; Davis, K H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c258t-2680683b89daf60242a533f5856f5f0f48054419455143fcd9dc86a5001b69f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Alternative Splicing</topic><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Biological Transport</topic><topic>Calcium - metabolism</topic><topic>Cattle</topic><topic>Cell Membrane - metabolism</topic><topic>Chromaffin Cells - metabolism</topic><topic>Exons</topic><topic>Kinetics</topic><topic>Molecular Sequence Data</topic><topic>Myocardium - metabolism</topic><topic>Protein Isoforms</topic><topic>Sequence Homology, Amino Acid</topic><topic>Sodium-Calcium Exchanger - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schneider, A S</creatorcontrib><creatorcontrib>Mah, S J</creatorcontrib><creatorcontrib>Farhadi, M</creatorcontrib><creatorcontrib>Grindi, E</creatorcontrib><creatorcontrib>Davis, K H</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of the New York Academy of Sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schneider, A S</au><au>Mah, S J</au><au>Farhadi, M</au><au>Grindi, E</au><au>Davis, K H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Calcium transport proteins in active secretory zones: Na-Ca exchange isoforms and exchanger kinetic properties in chromaffin granules and plasma membranes</atitle><jtitle>Annals of the New York Academy of Sciences</jtitle><addtitle>Ann N Y Acad Sci</addtitle><date>2002-10</date><risdate>2002</risdate><volume>971</volume><issue>1</issue><spage>142</spage><epage>144</epage><pages>142-144</pages><issn>0077-8923</issn><eissn>1749-6632</eissn><abstract>We have found that Na-Ca exchange influences Ca(2+) efflux, signal decay, and the rate of secretion in chromaffin cells. We now report the presence of two distinct splicing variant isoforms of Na-Ca exchange proteins in bovine chromaffin cells and their transport properties in chromaffin granules and plasma membrane vesicles.</abstract><cop>United States</cop><pmid>12438105</pmid><doi>10.1111/j.1749-6632.2002.tb04449.x</doi><tpages>3</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0077-8923
ispartof Annals of the New York Academy of Sciences, 2002-10, Vol.971 (1), p.142-144
issn 0077-8923
1749-6632
language eng
recordid cdi_proquest_miscellaneous_72685902
source MEDLINE; Wiley Online Library All Journals
subjects Alternative Splicing
Amino Acid Sequence
Animals
Biological Transport
Calcium - metabolism
Cattle
Cell Membrane - metabolism
Chromaffin Cells - metabolism
Exons
Kinetics
Molecular Sequence Data
Myocardium - metabolism
Protein Isoforms
Sequence Homology, Amino Acid
Sodium-Calcium Exchanger - chemistry
title Calcium transport proteins in active secretory zones: Na-Ca exchange isoforms and exchanger kinetic properties in chromaffin granules and plasma membranes
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T18%3A16%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Calcium%20transport%20proteins%20in%20active%20secretory%20zones:%20Na-Ca%20exchange%20isoforms%20and%20exchanger%20kinetic%20properties%20in%20chromaffin%20granules%20and%20plasma%20membranes&rft.jtitle=Annals%20of%20the%20New%20York%20Academy%20of%20Sciences&rft.au=Schneider,%20A%20S&rft.date=2002-10&rft.volume=971&rft.issue=1&rft.spage=142&rft.epage=144&rft.pages=142-144&rft.issn=0077-8923&rft.eissn=1749-6632&rft_id=info:doi/10.1111/j.1749-6632.2002.tb04449.x&rft_dat=%3Cproquest_cross%3E72685902%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=72685902&rft_id=info:pmid/12438105&rfr_iscdi=true