Significant genetic linkage of MDR1 polymorphisms at positions 3435 and 2677: Functional relevance to pharmacokinetics of digoxin

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Veröffentlicht in:	Pharmaceutical research 2002-10, Vol.19 (10), p.1581-1585
Hauptverfasser:	HORINOUCHI, Masanori, SAKAEDA, Toshiyuki, NAKAMURA, Tsutomu, MORITA, Yoshinori, TAMURA, Takao, AOYAMA, Nobuo, KASUGA, Masato, OKUMURA, Katsuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics Biological and medical sciences Cardiotonic agents Cardiovascular system Chi-Square Distribution Digoxin - blood Digoxin - pharmacokinetics Female Genetic Linkage Genotype Humans Male Medical sciences Middle Aged Pharmacology. Drug treatments Polymorphism, Genetic Polymorphism, Single Nucleotide - genetics
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