Long-term monitoring of cell-mediated immunity in disease-free breast cancer patients: a preliminary retrospective study

In 102 N– and 44 N+ disease-free breast cancer patients, lymphocytic populations and skin reaction of delayed hypersensitivity (SRDH) were monitored up to 266 months after mastectomy to find out whether they were similar or different from control values. In two selected groups of 34 N– and 11 N+ bre...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2002-09, Vol.56 (7), p.339-344
Hauptverfasser:	Nicolini, A., Carpi, A., Ferrari, P., Tartarelli, G., Anselmi, L., Metelli, M.-R., Gorini, I., Spinelli, C., Miccoli, P., Giardino, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Breast cancer Breast Neoplasms - blood Breast Neoplasms - immunology Breast Neoplasms - therapy Cell-mediated immunity Disease-free Disease-Free Survival Female Gynecology. Andrology. Obstetrics Humans Hypersensitivity, Delayed - immunology Immunity, Cellular - immunology Lymphocytes - blood Mammary gland diseases Medical sciences Middle Aged Monitoring, Immunologic - methods Retrospective Studies Tumors
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Zusammenfassung:	In 102 N– and 44 N+ disease-free breast cancer patients, lymphocytic populations and skin reaction of delayed hypersensitivity (SRDH) were monitored up to 266 months after mastectomy to find out whether they were similar or different from control values. In two selected groups of 34 N– and 11 N+ breast cancer patients, the whole 10 year follow-up was divided into three subintervals, each of them lasting 40 months and the time course of lymphocytic populations was evaluated. In the 102 N– patients, mean CD4+, CD8+, CD3+ values were lower ( P
ISSN:	0753-3322 1950-6007
DOI:	10.1016/S0753-3322(02)00243-3