Pachastrissamine, a Cytotoxic Anhydrophytosphingosine from a Marine Sponge, Pachastrissa sp
An anhydrophytosphingosine named pachastrissamine (3) has been isolated as a cytotoxic principle of a sponge, Pachastrissa sp., and the structure including the absolute configuration determined by spectroscopic and chemical analysis.
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Veröffentlicht in: | Journal of natural products (Washington, D.C.) D.C.), 2002-10, Vol.65 (10), p.1505-1506 |
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container_title | Journal of natural products (Washington, D.C.) |
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creator | Kuroda, Ikuma Musman, Musri Ohtani, Ikuko I Ichiba, Toshio Tanaka, Junichi Gravalos, Dolores Garcia Higa, Tatsuo |
description | An anhydrophytosphingosine named pachastrissamine (3) has been isolated as a cytotoxic principle of a sponge, Pachastrissa sp., and the structure including the absolute configuration determined by spectroscopic and chemical analysis. |
doi_str_mv | 10.1021/np010659y |
format | Article |
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Nat. Prod</addtitle><description>An anhydrophytosphingosine named pachastrissamine (3) has been isolated as a cytotoxic principle of a sponge, Pachastrissa sp., and the structure including the absolute configuration determined by spectroscopic and chemical analysis.</description><subject>anhydrophytosphingosine</subject><subject>Animals</subject><subject>Antineoplastic Agents - chemistry</subject><subject>Antineoplastic Agents - isolation & purification</subject><subject>Antineoplastic Agents - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Drug Screening Assays, Antitumor</subject><subject>General pharmacology</subject><subject>Humans</subject><subject>Marine</subject><subject>Medical sciences</subject><subject>Molecular Structure</subject><subject>natural products</subject><subject>Pachastrissa</subject><subject>Pachastrissamine</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>Porifera - chemistry</subject><subject>Spectrum Analysis - methods</subject><subject>Sphingosine - analogs & derivatives</subject><subject>Sphingosine - chemistry</subject><subject>Sphingosine - isolation & purification</subject><subject>Sphingosine - pharmacology</subject><subject>Tumor Cells, Cultured</subject><issn>0163-3864</issn><issn>1520-6025</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0MtqGzEUBmBRGhon7aIvUGbTQqDT6n5ZBtNbiGmKU7roQpzImnhSz2iqM4b47SNjE2dR6EpI-s7P4SfkNaMfGOXsYz9QRrVym2dkwhSntaZcPScTyrSohdXymJwg3lFKBXXqBTlmXDirlJyQ31cQloBjbhGha_v4voJquhnTmO7bUJ33y80ip2FZXnBYtv1twoKqJqeuwBnk7W0-pP62TD7NqnB4SY4aWGF8tT9Pyc_Pn66nX-vL71--Tc8va5BGj_UiUi5DaKxiUTgDTnGnDQfLQAKzWjX0RhllpBNWCEHBGhc4kzI2UWi9EKfk3S53yOnvOuLouxZDXK2gj2mN3nAthCqj_4PMWum43cKzHQw5IebY-CG3HeSNZ9RvK_ePlRf7Zh-6vuni4iD3HRfwdg8AA6yaDH1o8eCEK46p4uqda3GM94__kP94bYRR_vpq7n_Mfs1nF5J7c8iFgP4urXNfSv7Hgg8I7aOZ</recordid><startdate>20021001</startdate><enddate>20021001</enddate><creator>Kuroda, Ikuma</creator><creator>Musman, Musri</creator><creator>Ohtani, Ikuko I</creator><creator>Ichiba, Toshio</creator><creator>Tanaka, Junichi</creator><creator>Gravalos, Dolores Garcia</creator><creator>Higa, Tatsuo</creator><general>American Chemical Society</general><general>American Society of Pharmacognosy</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>F1W</scope><scope>FR3</scope><scope>H95</scope><scope>H99</scope><scope>L.F</scope><scope>L.G</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20021001</creationdate><title>Pachastrissamine, a Cytotoxic Anhydrophytosphingosine from a Marine Sponge, Pachastrissa sp</title><author>Kuroda, Ikuma ; Musman, Musri ; Ohtani, Ikuko I ; Ichiba, Toshio ; Tanaka, Junichi ; Gravalos, Dolores Garcia ; Higa, Tatsuo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a476t-de024ccf851e397a9529672a81a4a1865f0b575749383330a879c2144efe366d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>anhydrophytosphingosine</topic><topic>Animals</topic><topic>Antineoplastic Agents - chemistry</topic><topic>Antineoplastic Agents - isolation & purification</topic><topic>Antineoplastic Agents - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Drug Screening Assays, Antitumor</topic><topic>General pharmacology</topic><topic>Humans</topic><topic>Marine</topic><topic>Medical sciences</topic><topic>Molecular Structure</topic><topic>natural products</topic><topic>Pachastrissa</topic><topic>Pachastrissamine</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>Porifera - chemistry</topic><topic>Spectrum Analysis - methods</topic><topic>Sphingosine - analogs & derivatives</topic><topic>Sphingosine - chemistry</topic><topic>Sphingosine - isolation & purification</topic><topic>Sphingosine - pharmacology</topic><topic>Tumor Cells, Cultured</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kuroda, Ikuma</creatorcontrib><creatorcontrib>Musman, Musri</creatorcontrib><creatorcontrib>Ohtani, Ikuko I</creatorcontrib><creatorcontrib>Ichiba, Toshio</creatorcontrib><creatorcontrib>Tanaka, Junichi</creatorcontrib><creatorcontrib>Gravalos, Dolores Garcia</creatorcontrib><creatorcontrib>Higa, Tatsuo</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>ASFA: Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of natural products (Washington, D.C.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kuroda, Ikuma</au><au>Musman, Musri</au><au>Ohtani, Ikuko I</au><au>Ichiba, Toshio</au><au>Tanaka, Junichi</au><au>Gravalos, Dolores Garcia</au><au>Higa, Tatsuo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pachastrissamine, a Cytotoxic Anhydrophytosphingosine from a Marine Sponge, Pachastrissa sp</atitle><jtitle>Journal of natural products (Washington, D.C.)</jtitle><addtitle>J. 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subjects | anhydrophytosphingosine Animals Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Biological and medical sciences Drug Screening Assays, Antitumor General pharmacology Humans Marine Medical sciences Molecular Structure natural products Pachastrissa Pachastrissamine Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Porifera - chemistry Spectrum Analysis - methods Sphingosine - analogs & derivatives Sphingosine - chemistry Sphingosine - isolation & purification Sphingosine - pharmacology Tumor Cells, Cultured |
title | Pachastrissamine, a Cytotoxic Anhydrophytosphingosine from a Marine Sponge, Pachastrissa sp |
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