Pachastrissamine, a Cytotoxic Anhydrophytosphingosine from a Marine Sponge, Pachastrissa sp

An anhydrophytosphingosine named pachastrissamine (3) has been isolated as a cytotoxic principle of a sponge, Pachastrissa sp., and the structure including the absolute configuration determined by spectroscopic and chemical analysis.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2002-10, Vol.65 (10), p.1505-1506
Hauptverfasser:	Kuroda, Ikuma, Musman, Musri, Ohtani, Ikuko I, Ichiba, Toshio, Tanaka, Junichi, Gravalos, Dolores Garcia, Higa, Tatsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	anhydrophytosphingosine Animals Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Biological and medical sciences Drug Screening Assays, Antitumor General pharmacology Humans Marine Medical sciences Molecular Structure natural products Pachastrissa Pachastrissamine Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Porifera - chemistry Spectrum Analysis - methods Sphingosine - analogs & derivatives Sphingosine - chemistry Sphingosine - isolation & purification Sphingosine - pharmacology Tumor Cells, Cultured
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Beschreibung
Zusammenfassung:	An anhydrophytosphingosine named pachastrissamine (3) has been isolated as a cytotoxic principle of a sponge, Pachastrissa sp., and the structure including the absolute configuration determined by spectroscopic and chemical analysis.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np010659y