Electrochemotherapy, a new antitumor treatment: first clinical trial

Electrochemotherapy (ECT) is a new antitumor treatment which consists in delivering electric pulses to the tumor some minutes after an intravenous injection of bleomycin. We report here the first clinical trial of ECT, applied to patients with permeation nodules of head and neck squamous carcinomas....

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Veröffentlicht in:	Comptes rendus de l'Académie des sciences, Série III, Sciences de la vie Série III, Sciences de la vie, 1991, Vol.313 (13), p.613-618
Hauptverfasser:	Mir, L M, Belehradek, M, Domenge, C, Orlowski, S, Poddevin, B, Belehradek, Jr, J, Schwaab, G, Luboinski, B, Paoletti, C
Format:	Artikel
Sprache:	fre
Schlagworte:	Bleomycin - administration & dosage Bleomycin - therapeutic use Carcinoma, Squamous Cell - therapy Electric Stimulation Therapy - methods Electrochemistry Humans Injections, Intravenous Male Middle Aged Mouth Neoplasms - pathology Mouth Neoplasms - therapy Oropharyngeal Neoplasms - pathology Oropharyngeal Neoplasms - therapy Skin Neoplasms - secondary
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Zusammenfassung:	Electrochemotherapy (ECT) is a new antitumor treatment which consists in delivering electric pulses to the tumor some minutes after an intravenous injection of bleomycin. We report here the first clinical trial of ECT, applied to patients with permeation nodules of head and neck squamous carcinomas. ECT was well tolerated by patients, no serious incident occurred and a clear antitumor efficiency was found.
ISSN:	0764-4469