Expression of antigens on rat thymic epithelial cells during ontogenesis

The thymus plays an important role in the maturation and differentiation of T lymphocytes. Many of these functions have been attributed to the epithelial component. The thymic epithelial cells are thought to play a key role in thymocyte maturation either by cell-to-cell contact or under the influenc...

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Veröffentlicht in:Developmental and comparative immunology 1991, Vol.15 (4), p.443-450
Hauptverfasser: Mićić, Mileva, ElDeeb, Somaya, Čolić, Miodrag, Damjanović, Maja, Isakovic, Katarina
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container_end_page 450
container_issue 4
container_start_page 443
container_title Developmental and comparative immunology
container_volume 15
creator Mićić, Mileva
ElDeeb, Somaya
Čolić, Miodrag
Damjanović, Maja
Isakovic, Katarina
description The thymus plays an important role in the maturation and differentiation of T lymphocytes. Many of these functions have been attributed to the epithelial component. The thymic epithelial cells are thought to play a key role in thymocyte maturation either by cell-to-cell contact or under the influence of thymic hormones. In this study, the appearance of antigens specific for cortical, subcapsular and medullary rat thymic epithelial cells during embryologic and postnatal life is reported.
doi_str_mv 10.1016/0145-305X(91)90037-Y
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subjects Age Factors
Animals
Antibodies, Monoclonal - immunology
Antigens - biosynthesis
Biological and medical sciences
Epithelium - immunology
Female
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Gestational Age
Immunobiology
Lymphoid organs: ontogeny, organization, homing phenomenon
Male
Monoclonal antibodies
Ontogenesis
Rat thymus
Rats - growth & development
Rats - immunology
TE cells
Thymus Gland - cytology
Thymus Gland - embryology
Thymus Gland - growth & development
Thymus Gland - immunology
title Expression of antigens on rat thymic epithelial cells during ontogenesis
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