New Marine Diterpenoids from the Okinawan Soft Coral Clavularia koellikeri

Chemical investigation of the Okinawan soft coral Clavularia koellikeri resulted in the isolation of two new cembrane diterpenoids (1 and 2) and one new dollabelane diterpenoid, 3. Their structures were determined on the basis of the results of spectroscopic analysis. Compounds 1 and 3 were examined...

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Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 2002-10, Vol.65 (10), p.1441-1446
Hauptverfasser: IWASHIMA, Makoto, MATSUMOTO, Yuuki, TAKENAKA, Yosuke, IGUCHI, Kazuo, YAMORI, Takao
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Sprache:eng
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Zusammenfassung:Chemical investigation of the Okinawan soft coral Clavularia koellikeri resulted in the isolation of two new cembrane diterpenoids (1 and 2) and one new dollabelane diterpenoid, 3. Their structures were determined on the basis of the results of spectroscopic analysis. Compounds 1 and 3 were examined for in vitro growth-inhibition effects toward tumor cells.
ISSN:0163-3864
1520-6025
DOI:10.1021/np0200156