Anti-inflammatory activity of Pothomorphe peltata leaf methanol extract

The methanol extract of Pothomorphe peltata leaves, orally administered at the dose of 20 mg/kg (equivalent to 2.50 g dry plant/kg) body weight, exhibited a significant anti-inflammatory activity, comparable with phenylbutazone (80 mg/kg, p.o.), against adjuvant-carrageenan-induced edema in rats.

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Bibliographische Detailangaben
Veröffentlicht in:	Fitoterapia 2000-09, Vol.71 (5), p.556-558
Hauptverfasser:	Desmarchelier, C, Slowing, K, Ciccia, G
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Nerolidylcatechol Administration, Oral Animals Anti-inflammatory activity Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - pharmacology Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Carrageenan Edema - chemically induced Edema - prevention & control Female General pharmacology Humans Magnoliopsida Male Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phenylbutazone - pharmacology Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Leaves Plants, Medicinal Pothomorphe peltata Rats Rats, Wistar
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Beschreibung
Zusammenfassung:	The methanol extract of Pothomorphe peltata leaves, orally administered at the dose of 20 mg/kg (equivalent to 2.50 g dry plant/kg) body weight, exhibited a significant anti-inflammatory activity, comparable with phenylbutazone (80 mg/kg, p.o.), against adjuvant-carrageenan-induced edema in rats.
ISSN:	0367-326X
DOI:	10.1016/S0367-326X(00)00166-0