CLINICAL STUDY ON COUPLING INTERVAL OF VENTRICULAR PREMATURE CONTRACTION IN PATIENTS WITH ORGANIC HEART DISEASE

The characteristics of the coupling interval (CI) of ventricular premature con-traction (VPC) were studied in 100 patients with frequent VPCs using 24h ambulatory ECG recording. All R-R intervals were registered on computer to determine the mean value of CIs (Mean CI) and the standard deviation of C...

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Veröffentlicht in:	JAPANESE CIRCULATION JOURNAL 1991/12/20, Vol.55(12), pp.1174-1180
Hauptverfasser:	FUJIMOTO, YUKIHIRO, FUKUKI, MASAHARU, HIROKANE, YUJI, KOTAKE, HIROSHI, MASHIBA, HIROTO
Format:	Artikel
Sprache:	eng
Schlagworte:	Ambulatory ECG recording Antiarrhythmic agent Antiarythmic agents Biological and medical sciences Cardiac Complexes, Premature - physiopathology Cardiovascular system Coronary Disease - drug therapy Coronary Disease - physiopathology Coupling interval Disopyramide - therapeutic use Electrocardiography, Ambulatory Female Heart Diseases - drug therapy Heart Diseases - physiopathology Humans Hypertension - complications Male Medical sciences Mexiletine - therapeutic use Middle Aged Myocardial Contraction Organic heart disease Pharmacology. Drug treatments Ventricular Premature contraction
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Zusammenfassung:	The characteristics of the coupling interval (CI) of ventricular premature con-traction (VPC) were studied in 100 patients with frequent VPCs using 24h ambulatory ECG recording. All R-R intervals were registered on computer to determine the mean value of CIs (Mean CI) and the standard deviation of CIs (SD-CI). We compared the Mean CI and the SD-CI between idiopathic VPCs and VPCs with organic heart disease (OHD). In addition, we evaluated the efficacy of disopyramide (DP) and mexiletine (MX) and we examined the relationship between the efficacy of these drugs and the characteristics of CI. The Mean CI of VPCs with OHD was longer than that of idiopathic VPCs (530 vs. 494 msec, p
ISSN:	0047-1828 1347-4839
DOI:	10.1253/jcj.55.1174