Solid-phase synthesis of 2,4-diaminoquinazolines

A highly efficient and versatile solid‐phase synthesis of 2,4‐diaminoquinazoline library from 2,4‐dichloroquinazolines and amines using 3,5‐dimethoxy 4‐formylphenoxy‐polystyrene resin is described. © 2000 John Wiley & Sons, Inc. Biotechnol Bioeng (Comb Chem) 71:87–90, 2000/2001.

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Bibliographische Detailangaben
Veröffentlicht in:	Biotechnology and bioengineering 2000, Vol.71 (2), p.87-90
Hauptverfasser:	Wu, Zhengdong, Kim, Jooyoung, Soll, Richard M., Dhanoa, Dale S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chemistry combinatorial chemistry Combinatorial Chemistry Techniques drug discovery Exact sciences and technology General pharmacology Heterocyclic compounds Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings Magnetic Resonance Spectroscopy Medical sciences Miscellaneous Organic chemistry Pharmacology. Drug treatments Preparations and properties quinazolines Quinazolines - chemistry small molecule libraries Solid-phase synthesis
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Beschreibung
Zusammenfassung:	A highly efficient and versatile solid‐phase synthesis of 2,4‐diaminoquinazoline library from 2,4‐dichloroquinazolines and amines using 3,5‐dimethoxy 4‐formylphenoxy‐polystyrene resin is described. © 2000 John Wiley & Sons, Inc. Biotechnol Bioeng (Comb Chem) 71:87–90, 2000/2001.
ISSN:	0006-3592 1097-0290
DOI:	10.1002/1097-0290(200021)71:2<87::AID-BIT1>3.0.CO;2-W